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Moumoujus

CITRUS DEPRESSA FRUIT EXTRACT.

Valuable CAS - / SKIN CONDITIONING

Citrus depressa Fruit Extract, also known as Shekwasha, is a botanical powerhouse derived from the Okinawan citrus fruit, rich in beneficial phytochemicals. This extract is valued for its potent antioxidant capacity and its ability to contribute to skin brightening and reduce the impact of environmental stressors.

Summary

Antioxidant Skin-Conditioning Skin Brightening Anti-inflammatory Anti-aging

Science

Mechanism of Action

The efficacy of Citrus depressa Fruit Extract is primarily attributed to its high concentration of polymethoxylated flavones (PMFs), including nobiletin and tangeritin, along with other phenolics and flavanones. These compounds function as potent antioxidants, protecting the skin from oxidative damage. Furthermore, PMFs are understood to inhibit the production of matrix metalloproteinases (MMPs), thereby supporting skin integrity, and to mitigate UV-induced inflammation. The extract's essential oil components, such as limonene and γ-terpinene, contribute additional anti-inflammatory properties, promoting a more balanced and soothed complexion.

Research

Clinical Evidence

Low confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The natural pH of Citrus depressa fruit juice itself typically ranges from approximately 2.30 to 3.98, indicating an acidic profile. Specific optimal pH ranges for the stability of the cosmetic extract in formulations were not directly identified in the research data.

Conflicts

  • Ingredients that may cumulatively elevate levels of phototoxic compounds such as 5-methoxypsoralen (5-MOP) or 7-methoxycoumarin in the final formulation.
  • Ingredients that may cumulatively elevate levels of sensitizing monoterpenes like limonene or citral in the final formulation.
  • Strong oxidizing agents, which can degrade delicate botanical compounds.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
0.0015%
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) Expert Panel has deemed Citrus fruit-derived ingredients, including Citrus depressa Fruit Extract, safe for both rinse-off and leave-on cosmetic products, provided formulations are non-sensitizing and non-irritating. A critical restriction for leave-on products is that the concentration of 5-methoxypsoralen (5-MOP) must not exceed 0.0015% (15 ppm) due to its known phototoxic potential. Manufacturers must meticulously manage constituent levels of limonene, citral, other monoterpenes, and furocoumarins, especially when combining multiple botanicals, to prevent hazardous concentrations. The U.S. FDA recognizes Citrus fruits as Generally Recognized As Safe (GRAS) for direct food use.

Your Skin

Skin Compatibility

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Citrus depressa Fruit Extract offers valuable antioxidant, brightening, and anti-inflammatory benefits, contingent on strict formulation controls to ensure safety regarding phototoxic and sensitizing constituents.

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