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CITRUS AURANTIUM PEEL EXTRACT.

Valuable CAS 72968-50-4 / PERFUMING

Derived from bitter orange peel, Citrus Aurantium Peel Extract is a multi-functional botanical ingredient rich in beneficial bioactive compounds. It actively works to protect and revitalize the skin, offering significant antioxidant and anti-inflammatory properties. This extract also possesses antimicrobial capabilities, making it a valuable addition to precision skincare formulations.

Summary

Antioxidant Anti-inflammatory Antibacterial Skin Conditioning Gentle Exfoliant Perfuming Fragrance Enhancer Viscosity Controlling

Science

Mechanism of Action

This extract operates through a complex blend of bioactive compounds, including flavonoids, phenolic acids, and vitamin C. Its primary actions involve reducing oxidative stress on the skin by neutralizing free radicals and exerting anti-inflammatory effects through the reduction of inflammatory markers such as IL-6 and TNF-α. Furthermore, it demonstrates antimicrobial activity against various skin pathogens, acts as a skin conditioning agent to enhance texture and appearance, and may provide a gentle exfoliating effect due to its natural fruit acid content.

Research

Clinical Evidence

Medium confidence
Effective range N/A
Optimal

N/A

Transparency

Dusting Analysis

Not commonly dusted

Citrus Aurantium Peel Extract possesses a range of demonstrable bioactive properties at relevant concentrations, making it a functional ingredient typically included for its intended benefits rather than as a negligible 'dusting' component.

The Formula

Formulation

Solubility
Both
Optimal pH 4 – 6
0 7 14

Stability

Optimal stability is achieved within an acidic pH range of 4.0 to 6.0, aligning with the reported aqueous bitter orange peel extract pH of 4.30.

Conflicts

  • Avoid formulating in leave-on products where 5-methoxypsoralen (5-MOP) concentration exceeds 0.0015% (15 ppm) due to photosensitivity risks.
  • Not recommended for use on broken or irritated skin.

Safety

Safety Profile

CIR Status
Safe with restrictions
Max tested
10%
Sensitization risk Moderate

The CIR Expert Panel considers citrus peel-derived ingredients safe in cosmetics, including leave-on products, when formulated to be non-sensitizing and non-irritating, provided the 5-MOP content in leave-on products is below 0.0015%. Due to potential photosensitivity, daily application of sunscreen is advised when using products containing this extract. Sensitive individuals may experience irritation or allergic reactions, necessitating prior patch testing. The FDA generally recognizes related orange extracts as safe for human food use.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Citrus Aurantium Peel Extract is a valuable ingredient offering potent antioxidant, anti-inflammatory, and antimicrobial benefits, requiring meticulous formulation and consumer guidance on photosensitivity for optimal and safe use.

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