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Moumoujus

CITRUS AURANTIUM LEAF EXTRACT.

Valuable CAS 72968-50-4 / PERFUMING

Derived from the leaves of the bitter orange tree, Citrus Aurantium Leaf Extract is a multi-functional botanical celebrated for its potent antioxidant, anti-aging, and skin-brightening properties. This extract aids in enhancing skin's structural integrity, evening tone, and providing protective benefits.

Summary

Antioxidant Anti-aging Skin Brightening Antimicrobial Anti-inflammatory

Science

Mechanism of Action

This extract functions as a comprehensive skin rejuvenator. Its rich content of flavonoids, ascorbic acid, and phenolic compounds actively scavenges free radicals, mitigating oxidative stress. It supports skin's youthful appearance by inhibiting key enzymes such as collagenase, elastase, and matrix metalloproteinases (MMPs) that degrade structural proteins, while also promoting collagen synthesis. Skin brightening is achieved through its inhibitory action on tyrosinase, the enzyme crucial for melanin production. Furthermore, it offers antimicrobial defense against various pathogens and modulates inflammatory responses by suppressing pro-inflammatory cytokines.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Demonstrated 40.5% inhibition of cellular tyrosinase activity and reduced melanin content in HEMn cells by 36.1% in vitro.
  2. 02 Achieved 72.8% inhibition of cellular tyrosinase activity and a significant reduction in melanin content in HEMn cells, leaving only 3.5% of baseline melanin.
  3. 03 Determined as the half maximal inhibitory concentration (IC50) for cellular tyrosinase activity, indicating potent melanin-reducing potential.
  4. 04 Established as the half maximal inhibitory concentration (IC50) for anticollagenase activity, suggesting efficacy in preserving skin collagen.
  5. 05 Identified as the half maximal inhibitory concentration (IC50) for antielastase activity, supporting skin elasticity.
  6. 06 Found to be the half maximal inhibitory concentration (IC50) for anti-matrix metalloprotein-1 activity, crucial for maintaining dermal integrity.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

For optimal stability, the extract should be protected from light, typically requiring packaging in dark containers. Due to the general photosensitivity associated with citrus extracts, careful formulation and user guidance on sunscreen use during daytime application are essential.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not specifically reviewed Citrus Aurantium Leaf Extract. While generally considered safe and well-tolerated for topical use, it shares common citrus extract concerns regarding furocoumarins and potential photosensitivity. Therefore, consistent use of sunscreen is advised when incorporated into daytime routines. A patch test is recommended for individuals with sensitive skin, as it may cause irritation or allergic reactions in rare cases.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
No Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Citrus Aurantium Leaf Extract is a valuable botanical ingredient, offering demonstrated benefits in skin brightening, anti-aging, and antioxidant defense, with careful consideration for photosensitivity in product formulation and usage.

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