CISTUS INCANUS EXTRACT.

Cistus incanus extract operates primarily by blocking the corticotropin releasing hormone receptor 1 (CRH-R1), effectively inhibiting the stress-induced activation of NF-κB and subsequent production of pro-inflammatory cytokines such as IL1-β, IL6, and TNF-α. This mechanism directly reduces neurogenic inflammation and decelerates skin aging linked to psychological stress. Furthermore, its rich polyphenolic content, including myricitrin, confers potent antioxidant properties, safeguarding skin from free radical damage. The extract also demonstrates tyrosinase inhibition for anti-hyperpigmentation and offers natural UV-protective activity.