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CISTANCHE TUBULOSA STEM EXTRACT.

Valuable CAS - / SKIN CONDITIONING

A potent botanical powerhouse derived from the desert hyacinth, specifically utilized in precision skincare for its high concentration of phenylethanoid glycosides. It serves as a dual-action agent that simultaneously reinforces the skin's structural matrix while providing robust defense against environmental oxidative stress.

Antioxidant Humectant Anti-aging Skin-brightening UV-protection booster

Science

The extract operates through a multi-pathway approach: it optimizes the skin's antioxidant profile by stimulating Superoxide Dismutase (SOD) activity and scavenging free radicals. On a structural level, it triggers the synthesis of endogenous hyaluronic acid and modulates collagen metabolism to maintain dermal density, while its unique iridoid and glycoside content offers natural UV-absorbing properties and inhibits tyrosinase to regulate melanin production.


Research

Medium confidence
Effective range ≥0.012%
Optimal

N/A

Key findings

  1. 01 Demonstrated significant DPPH radical scavenging activity in vitro, confirming its status as a high-performance antioxidant.
  2. 02 Observed measurable improvements in hyaluronic acid production and biomarkers related to moisture retention and collagen metabolism.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its potency and cost, this extract is frequently included in 'label-only' concentrations. Formulations containing less than 0.1% may provide basic antioxidant support but likely fail to trigger the collagen-metabolism and hyaluronic acid stimulation benefits observed in higher-concentration in vitro studies.


The Formula

Solubility
Water
Optimal pH 4 – 8.5
0 7 14

Stability

The extract exhibits excellent long-term stability (up to 48 months at standard conditions) when maintained in an acidic environment below pH 8.5.

Synergies

  • Vitamin C
  • Hyaluronic Acid
  • Ferulic Acid

Conflicts

  • High-alkalinity formulations (pH > 8.5)

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

While EFSA raised concerns regarding high-dose oral ingestion (novel food status), topical application has been validated via human patch testing to be non-stimulating and safe for cosmetic use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A highly stable, multi-functional botanical that excels in photo-protection and deep hydration, provided it is formulated at an efficacious concentration.


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