Science
Mechanism of Action
Cistanche Tubulosa Extract operates through several key pathways. It functions as a potent antioxidant by enhancing superoxide dismutase (SOD) activity, thereby protecting skin cells from oxidative stress. Its anti-aging benefits stem from its ability to enhance the skin barrier function, maintain skin matrix structure, and increase hydroxyproline levels, which are crucial for collagen fiber quantity and skin elasticity. The extract provides significant moisturizing capabilities due to its excellent water-holding ability and the presence of natural humectants like mannitol, betaine, and allantoin. It also contributes to skin brightening and tone regulation by modulating tyrosinase activity and inhibiting melanin production via its phenethyl alcohol glycosides. Furthermore, these phenethyl glycosides exhibit UV-absorbing properties, helping to mitigate skin damage from ultraviolet radiation, while polysaccharides from the Cistanche genus are known to protect skin cells exposed to UVB. The extract also supports a healthy inflammatory response and promotes cell proliferation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Topical application significantly reduced water evaporation from the skin, demonstrating excellent water-holding ability and suitability for moisturizing cosmetic formulations.
- 02 In vitro studies showed a positive impact on maintaining skin matrix structure, with beneficial changes in the expression levels of biomarkers associated with collagen metabolism and moisture retention. Phenethyl glycosides inhibited UVB-induced tyrosinase activity and regulated mRNA transcription levels of related genes, contributing to skin tone brightening and evening out complexion.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
The activity of Cistanche Tubulosa Extract is stabilized within a pH range of 4.0 to 8.5. Optimal activity is observed at pH levels below 6.0, with activity gradually decreasing as pH rises, and declining significantly when pH exceeds 9.0.
Safety
Safety Profile
A cosmetic patent asserts the extract's safety based on cytotoxicity and general safety tests, claiming it is free of stimulation. While the European Food Safety Authority (EFSA) has conducted a safety assessment for Cistanche tubulosa stems as a novel food, and genotoxicity studies exist for health food products, specific cosmetic ingredient review status or maximum concentration guidance from the Cosmetic Ingredient Review (CIR), Scientific Committee on Consumer Safety (SCCS), or FDA for cosmetic applications were not found.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Cistanche Tubulosa Extract is a valuable botanical ingredient offering a spectrum of benefits, from potent antioxidant protection and significant hydration to anti-aging and skin-brightening effects, making it suitable for a wide array of precision skincare formulations.
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References
Sources