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CISSAMPELOS PAREIRA BARK EXTRACT.

Valuable CAS 93333-87-0 / SKIN CONDITIONING

A botanical powerhouse rich in specialized pectin (PCP) that functions as both a structural humectant and a cellular antioxidant. It is prized in precision skincare for its dual ability to lock in moisture and shield dermal fibroblasts from oxidative stress.

Humectant Antioxidant Skin-conditioning agent Anti-inflammatory

Science

The extract operates through its high pectin content, which exhibits exceptional water-absorbing and gelling properties to reinforce the skin's moisture barrier and elasticity. On a cellular level, its phytochemical profile—comprising alkaloids, flavonoids, and tannins—neutralizes reactive oxygen species, specifically protecting fibroblasts from hydrogen peroxide-induced damage.


Research

High confidence
Effective range 0.5–1%
Optimal

0.5%

Key findings

  1. 01 An 8-week clinical trial demonstrated that topical application of 0.5% and 1.0% concentrations significantly increased skin hydration and structural elasticity compared to baseline.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

While many formulas include this extract at trace levels for marketing claims, clinical data suggests a minimum threshold of 0.5% is required to achieve measurable improvements in skin hydration and elasticity.


The Formula

Solubility
Water
Optimal pH 3.5 – 4.5
0 7 14

Stability

The pectin component is naturally acidic (pH ~3.74). While physically stable through heating-cooling cycles, high temperatures may cause minor fluctuations in viscosity and antioxidant potency.

Synergies

  • Hyaluronic Acid
  • Vitamin C
  • Glycerin

Safety

CIR Status
Not reviewed
Max tested
1%
Sensitization risk Low

Human patch tests and clinical trials at 1.0% concentration reported zero instances of irritation or sensitization.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A scientifically-backed botanical that delivers measurable improvements in elasticity and hydration when formulated at concentrations of 0.5% or higher.


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