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CIMICIFUGA DAHURICA ROOT/FORSYTHIA VIRDISSIMA FRUIT/GLYCYRRHIZA GLABRA ROOT/PAEONIA LACTIFLORA ROOT/PLATYCODON GRANDIFLORUM ROOT/PUERARIA LOBATA ROOT EXTRACT.

Valuable CAS - / HUMECTANT, SKIN CONDITIONING

This complex blend of botanical root and fruit extracts functions primarily as a skin conditioning agent and humectant. It is recognized for its potential to combat photoaging, reduce oxidative stress, and support skin barrier health through various antioxidant and anti-inflammatory mechanisms.

Skin conditioning Humectant Antioxidant Anti-inflammatory Collagen boosting Photoaging prevention

Science

This ingredient complex operates as a humectant, efficiently attracting and retaining moisture, thereby contributing to skin hydration and overall condition. Individual components within the blend offer targeted actions: Cimicifuga dahurica root extract provides antioxidant benefits. Platycodon grandiflorum exhibits both anti-inflammatory and antioxidant activities, with its saponins demonstrated to alleviate atopic dermatitis-like skin lesions by suppressing NF-κB and STAT1 signaling, concurrently activating the Nrf2/ARE-mediated heme oxygenase-1 pathway. Pueraria lobata extract further contributes anti-inflammatory and antioxidant effects, stimulates collagen production, and helps maintain hyaluronic acid levels, collectively supporting anti-photoaging actions via the Nrf2 pathway.


Research

Low confidence
Effective range 0.0025–0.01%
Optimal

N/A

Key findings

  1. 01 An in vitro study demonstrated that Pueraria montana var. lobata ethanol extract, a component of this blend, at concentrations between 0.0025% and 0.01% (equivalent to 25-100 μg/mL), significantly increased collagen production and reduced intracellular reactive oxygen species (ROS) levels in human dermal fibroblasts exposed to UVB-irradiation, effectively inhibiting photoaging processes.

Transparency

Not commonly dusted

The Formula

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Specific optimal pH range or general stability considerations for the entire complex are not documented. However, given that components like Platycodon grandiflorum are typically utilized as water extracts, water solubility is expected for the botanical extracts in this complex.


Safety

CIR Status
Not reviewed
Sensitization risk Unknown

The Cosmetic Ingredient Review (CIR) and SCCS have not conducted specific safety assessments for this complex ingredient. The Good Scents Company reports 'Not determined' for the oral, parenteral, dermal, and inhalation toxicity of the blend, indicating a lack of comprehensive safety data.


Your Skin

No Normal
No Dry
No Oily
No Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

This botanical complex offers valuable antioxidant and anti-inflammatory support, with specific evidence for a key component in promoting collagen synthesis and mitigating photoaging in human dermal fibroblasts.


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