Science
Mechanism of Action
This ingredient delivers a complex blend of bioactive compounds, including carotenoids (such as bixin and norbixin), tocotrienols (a form of Vitamin E), flavonoids, and other polyphenols, to the skin. These constituents exert potent antioxidant activity, effectively neutralizing free radicals and mitigating oxidative stress from environmental factors. Annatto also supports the skin's natural defense mechanisms against UV-induced damage, provides anti-inflammatory benefits to reduce redness and irritation, and offers nourishing properties for overall skin health. Specific research indicates that bixin may contribute to accelerated wound healing and enhanced skin cell regeneration.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
CI 75120 is available in oil-soluble forms (primarily bixin) and water-soluble forms (norbixin salts). Oil-soluble bixin demonstrates thermal stability under low to moderate heat. Water-soluble forms are stable in alkaline aqueous solutions, with an optimal pH of approximately 8.0, but will precipitate in acidic conditions below pH 7. While generally stable to heat and oxidation, degradation can occur at temperatures exceeding 125°C. Water-soluble forms are also susceptible to decomposition and color fading upon direct sunlight exposure.
Conflicts
- acidic solutions (for water-soluble forms)
- direct sunlight exposure (for water-soluble forms)
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has deferred evaluation of CI 75120, as the FDA has already approved Annatto as a color additive for foods, drugs, and cosmetics, including for use in the eye area. In the European Union, it is listed in Annex IV of the Cosmetics Regulation, permitting its use as a coloring agent in all cosmetics with specific maximum concentrations. While generally safe, individuals with known allergies to plants in the Bixaceae family may experience allergic reactions. Reports regarding skin and eye irritation are conflicting, with some data suggesting potential irritation, while other sources classify it as having limited or no irritant potential.
Your Skin
Skin Compatibility
Our Assessment
Verdict
CI 75120 is a valuable ingredient for Moumoujus, offering both a natural orange-red coloration and a spectrum of skin benefits through its antioxidant, anti-inflammatory, and nourishing compounds, supporting overall skin health and rejuvenation.
Related
Similar Ingredients
Finding similar ingredients…