Science
Mechanism of Action
This carotenoid functions primarily as a first-line defense antioxidant by efficiently quenching reactive oxygen species, particularly singlet oxygen, generated by UV radiation and pollution. Beyond its protective capabilities, CI 40800 acts as a precursor to vitamin A, a vital nutrient for maintaining healthy skin. Topically, it supports the skin's barrier integrity and is observed to enhance the appearance of dry or damaged skin by mitigating flaking and restoring suppleness.
Research
Clinical Evidence
Medium confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
CI 40800 exhibits chemical instability, being highly susceptible to degradation from heat, light, and oxygen. These environmental factors can accelerate isomerization and oxidative processes, diminishing its efficacy and potentially causing undesirable color shifts in the final product. To maintain stability and potency, strategic formulation is crucial, including the incorporation of synergistic antioxidant co-systems (e.g., tocopherols), processing under oxygen-limited conditions, and packaging in opaque or UV-protective containers. Due to its oil-solubility, it optimally integrates into the lipid phase of emulsions, as well as anhydrous oil-based serums, balms, and sticks.
Synergies
- Tocopherols
Conflicts
- Retinol and other Vitamin A derivatives (may lead to irritation)
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) has deferred its evaluation of CI 40800, acknowledging that the FDA has already assessed its safety. Beta-carotene demonstrates an excellent safety profile for topical use within cosmetic applications. The FDA categorizes Beta-Carotene as a color additive exempt from certification, deeming it safe for use in foods, drugs, and cosmetics, including products intended for the eye area. In the EU, it is recognized under the CosIng database as both CI 40800 (colorant) and beta-carotene (antioxidant), and its use as a coloring agent is permitted in all cosmetic categories as per Annex IV of the EC Cosmetics Regulation, with specific maximum concentrations and permitted application areas outlined.
Your Skin
Skin Compatibility
Our Assessment
Verdict
CI 40800 is a valuable multifunctional ingredient, offering robust antioxidant protection, essential barrier support, and natural tinting capabilities, making it a strong asset for promoting overall skin health and vitality.
Related
Similar Ingredients
Finding similar ingredients…