Science
Mechanism of Action
This ingredient operates on several biological pathways to enhance skin health. Its high flavonoid content provides robust antioxidant defense by neutralizing reactive oxygen species and inhibiting nitric oxide production. It also significantly calms inflammatory responses by downregulating IL-1β expression and potentially inhibiting the NF-κB pathway, as well as suppressing the NLRP3 inflammasome through ASC oligomerization inhibition. Beyond these protective actions, it actively supports skin moisture, reinforces the hydrolipidic barrier, and encourages cellular regeneration and elasticity. Furthermore, it can boost microcirculation, fostering a more vibrant complexion, and has been observed to stimulate hair growth by enhancing dermal papilla cell proliferation and promoting the anagen phase.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 A water extract demonstrated anti-inflammatory effects by suppressing IL-1β production in LPS-primed macrophages at concentrations between 30 and 300 µg/ml.
- 02 A water fraction was shown to stimulate hair shaft production and accelerate the anagen phase in telogen hair follicles, alongside promoting the differentiation and proliferation of epidermal matrix and stem cells in a mouse model.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
Precise optimal pH range for its stability is not detailed in the available research.
Safety
Safety Profile
While generally well-tolerated and rarely causing irritation, individuals with known sensitivities to other chrysanthemum varieties should perform a patch test prior to widespread use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Chrysanthemum Zawadskii Water is a valuable botanical ingredient, offering comprehensive benefits from robust antioxidant and anti-inflammatory protection to enhanced hydration, skin regeneration, and even hair growth support.
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References
Sources