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Moumoujus

CHRYSANTHEMUM ZAWADSKII SPROUT EXTRACT.

Valuable

Chrysanthemum Zawadskii Sprout Extract is a multifaceted botanical ingredient celebrated for its regenerative properties. Rich in flavonoids, it actively combats oxidative stress and inflammation, while promoting skin soothing and microcirculation. Furthermore, it demonstrates promising efficacy in stimulating hair growth by targeting follicular dermal papilla cells.

Summary

Antioxidant Soothing Anti-inflammatory Hair Growth Promoter Skin Regeneration

Science

Mechanism of Action

This extract functions primarily through its high flavonoid content, which is instrumental in mitigating inflammatory responses and encouraging cellular regeneration. It counteracts oxidative damage, enhances dermal microcirculation, and provides significant calming benefits by reducing redness and irritation. The ingredient also supports the integrity of the skin's hydrolipidic barrier. For hair, its mechanism involves stimulating the proliferation of follicular dermal papilla cells, upregulating key growth-promoting proteins like phosphorylated protein kinase B (p-Akt), p-ERK, and B-cell lymphoma 2 (Bcl-2), while decreasing the pro-apoptotic protein Bax. Its anti-inflammatory effects are largely attributed to the inhibition of the NF-κB signaling pathway.

Research

Clinical Evidence

High confidence
Effective range 0.1–10%
Optimal

N/A

Key findings

  1. 01 In concentrations ranging from 0.1 to 10 ppm, the extract significantly stimulates the proliferation of follicular dermal papilla cells, indicating a clear potential for promoting hair growth.
  2. 02 It exhibits potent antioxidant activity, with an IC50 of 186.04 µg/ml in DPPH assays and 94.56 µg/ml in ABTS assays, effectively neutralizing free radicals.
  3. 03 Further studies demonstrate robust anti-inflammatory effects, marked by the suppression of reactive oxygen species (ROS) and nitric oxide (NO) production, along with the downregulation of iNOS and IL-1β expression.

Transparency

Dusting Analysis

Not commonly dusted

Insufficient data to assess dusting potential.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

While not yet reviewed by CIR or SCCS, Chrysanthemum Zawadskii Flower Extract is generally regarded as a safe ingredient for cosmetic applications. Dermatological assessments suggest a low incidence of allergic reactions or skin irritation, making it suitable even for sensitive skin types. However, as with many natural extracts, a preliminary patch test is recommended for individuals with known sensitivities, particularly to other chrysanthemum varieties.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

With its proven antioxidant, anti-inflammatory, and hair growth-promoting properties, coupled with excellent skin compatibility and low irritation potential, Chrysanthemum Zawadskii Sprout Extract is a valuable botanical asset for comprehensive skin and hair formulations.

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