CHRYSANTHEMUM ZAWADSKII FLOWER EXTRACT.

This extract operates on multiple biological pathways crucial for skin and hair health. Rich in flavonoids, it powerfully combats oxidative stress by scavenging reactive oxygen species and inhibiting nitric oxide production. Its anti-inflammatory action is mediated through the downregulation of pro-inflammatory mediators like iNOS and IL-1β, and inhibition of the NF-κB signaling pathway, effectively reducing redness and irritation. On a cellular level, it stimulates the proliferation of follicular dermal papilla cells, increasing cellular activity and expression of key proteins (p-Akt, p-ERK, B-cell lymphoma 2), while decreasing pro-apoptotic factors (Bax) to promote robust hair growth. Additionally, it aids in maintaining the hydrolipidic barrier and enhancing microcirculation for a healthier complexion.