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CHRYSANTHEMUM PARTHENIUM FLOWER EXTRACT.

Valuable CAS 89997-65-9 / SKIN CONDITIONING

Chrysanthemum Parthenium Flower Extract is a botanical ingredient recognized for its robust antioxidant and anti-inflammatory capabilities. When precisely formulated as a parthenolide-depleted extract, it effectively combats oxidative stress, visibly soothes skin irritation and redness, and offers protective benefits against UV damage while potentially inhibiting melanin production for an even skin tone.

Summary

Antioxidant Skin-Conditioning Agent Soothing

Science

Mechanism of Action

This extract primarily functions as a potent antioxidant, neutralizing free radicals and significantly reducing oxidative stress in skin cells. Its inherent anti-inflammatory properties help to calm irritated skin and diminish visible signs of redness. Furthermore, when specifically processed to be parthenolide-depleted, it demonstrates the capacity to shield the skin from UV-induced damage and may contribute to a more uniform complexion by downregulating tyrosinase expression, a key enzyme in melanin biosynthesis.

Research

Clinical Evidence

High confidence
Effective range 1–2.5%
Optimal

1%

Key findings

  1. 01 Clinical studies indicate that a 1.0% concentration of this extract is optimal for significantly reducing oxidative stress in skin cells.
  2. 02 Concentrations below 2.5% have been shown to exhibit the strongest antioxidant properties, leading to the greatest reduction in cellular oxidative stress.

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
1%
Red flag below
5%

Specific clinical data outlines optimal and effective concentrations for this ingredient, indicating it is typically included at functional levels rather than as a 'dusting' ingredient for marketing claims. However, exceeding 5.0% has been shown to induce oxidative stress, negating its benefits.

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • The naturally occurring compound parthenolide, a sesquiterpene lactone present in the extract, can cause significant skin sensitization and irritation. Therefore, it is paramount to utilize parthenolide-depleted extracts in cosmetic formulations to prevent potential adverse reactions.

Safety

Safety Profile

CIR Status
Not reviewed
Max tested
5%
Sensitization risk High

The presence of parthenolide in non-depleted extracts presents a high risk of sensitization, irritation, inflammation, and dryness for skin. Formulators must exclusively use parthenolide-depleted versions to ensure product safety and mitigate adverse skin reactions. Moreover, concentrations exceeding 5.0% have been observed to induce oxidative stress in skin cells, counteracting its beneficial effects.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Chrysanthemum Parthenium Flower Extract is a valuable ingredient for its robust antioxidant, anti-inflammatory, and protective properties, provided it is rigorously processed to be parthenolide-depleted and formulated within effective concentration limits to ensure efficacy and minimize irritation risk.

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