Science
Mechanism of Action
This flower oil acts through multiple pathways to enhance skin health. It is rich in polyphenols such as quercetin, luteolin, and apigenin, which effectively neutralize free radicals, offering protection against premature aging, pollution, and UV damage. Beta-carotene and Vitamin A contribute to cellular regeneration and waste removal. Additionally, it functions as a natural astringent, helping to refine pore appearance and balance skin tone. Its antimicrobial activity against bacteria like Staphylococcus aureus and Propionibacterium acnes, along with antifungal properties, supports a clearer complexion. The oil also possesses anti-glycation and anti-collagenase effects, preserving skin elasticity, and its soothing qualities reduce redness and swelling, reinforcing the skin barrier.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Chrysanthemum morifolium essential oil demonstrated notable antioxidant potential with an IC50 of 2.59 mg/mL.
- 02 In vitro studies utilizing Chrysanthemum morifolium flower extracts (hydroglycolic solvent blend) revealed significant antioxidant, anti-glycation, and anti-collagenase activities.
- 03 Chrysanthemum morifolium essential oils, at concentrations ranging from 6.25 to 100 mg/mL, were observed to alleviate P. acnes-induced inflammation in THP-1 cells during an in-vitro study.
- 04 Safety evaluations confirmed that Chrysanthemum morifolium flower extracts did not induce skin irritation or sensitization in vitro, with specific in chemico testing showing no sensitization at 0.5 mg/mL.
- 05 Adding 0.5% water extract of chrysanthemum to a beauty cream effectively reduced melanin levels, indicating potential as a natural brightening agent.
- 06 A concentrated Chrysanthemum (12:1) Botanical Extract is suggested for use at 0.5-2% in facial creams and lotions to comfort the skin and promote an even-looking complexion.
Transparency
Dusting Analysis
No specific data on dusting behavior or thresholds were provided for Chrysanthemum Morifolium Flower Oil within the available research, thus it cannot be assessed.
The Formula
Formulation
Stability
Chrysanthemum morifolium volatile oil is a liquid at room temperature and does not dissolve in water. It exhibits solubility in various organic solvents including ethyl acetate, 95% ethanol, isopropyl alcohol, acetone, n-octanol, n-hexane, and n-heptane. Its antibacterial activity stability showed no significant difference following temperature and UV treatments.
Safety
Safety Profile
In vitro and in chemico safety evaluations of Chrysanthemum morifolium flower extracts have indicated no evidence of skin irritation or sensitization. While Chrysanthemum indicum (a related species) essential oil showed no acute oral toxicity or mutagenicity in animal studies, comprehensive toxicological data for Chrysanthemum Morifolium Flower Oil specifically are limited, and it has not been reviewed by CIR, SCCS, or FDA.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Chrysanthemum Morifolium Flower Oil is a valuable multi-functional ingredient, demonstrating promising antioxidant, anti-inflammatory, and protective benefits with a low risk of irritation, though further human clinical trials for the oil are warranted to fully confirm efficacy and safety in vivo.
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