Science
Mechanism of Action
This extract functions as a potent antioxidant by actively neutralizing harmful reactive oxygen species (ROS), primarily due to its rich content of flavonoids such as linarin and luteolin, which offer defense against environmental stressors like UV radiation and pollution. It exerts anti-inflammatory effects by inhibiting UV-induced inflammation and reducing key inflammatory mediators including IL-1, IL-6, TNF-α, and nitric oxide (NO), thereby calming irritation and diminishing redness. Furthermore, Chrysanthemum Indicum Extract exhibits antibacterial and antiviral properties, which can aid in managing acne and inhibiting the proliferation of various detrimental bacteria. It contributes to skin conditioning by promoting hydration, enhancing skin texture and elasticity, and has been observed to stimulate collagen production. Its ability to dose-dependently inhibit tyrosinase activity and reduce melanin levels supports skin brightening, while also assisting in balancing the skin's natural microbiome.
Research
Clinical Evidence
Medium confidence0.5% (for melanin reduction)
Key findings
- 01 In human volunteers, cosmetic formulations containing 0.5% Chrysanthemum indicum water extract time-dependently reduced melanin levels over 6 weeks, indicating its potential as a natural skin-brightening agent.
- 02 Aqueous extract of Chrysanthemum indicum inhibited the growth of Staphylococcus aureus in vitro.
- 03 Aqueous extract of Chrysanthemum indicum inhibited the growth of Pseudomonas aeruginosa in vitro.
- 04 Aqueous extract of Chrysanthemum indicum inhibited the growth of Escherichia coli, Streptococcus pneumoniae, and Shigella flexneri in vitro.
- 05 Chrysanthemum indicum essential oil showed moderate antibacterial activity against Gram-positive bacteria including Bacillus subtilis, Streptococcus agalactiae, and Streptococcus pyogenes in vitro.
- 06 The aqueous fraction of Chrysanthemum indicum flowers demonstrated significant antioxidant activity in vitro.
- 07 The ethanolic extract of Chrysanthemum indicum flowers exhibited significant antioxidant activity in vitro.
Transparency
Dusting Analysis
Information not available in provided research data.
The Formula
Formulation
Safety
Safety Profile
No specific CIR safety assessment for Chrysanthemum Indicum Extract was found. However, related forms like *Chrysanthemum indicum* flower oil showed no acute oral toxicity or mutagenicity at 2,000 mg/kg body weight/day. 'Chrysanthemum Indicum Callus Culture Extract' is generally considered safe with rare instances of allergic reactions or skin irritation. EWG rates concerns for 'Chrysanthellum Indicum Extract' as low across various toxicity categories.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Chrysanthemum Indicum Extract is a valuable botanical ingredient offering diverse benefits from antioxidant protection and anti-inflammatory action to skin brightening and microbial balancing, suitable for a wide range of skin types.
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