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Moumoujus

CHRYSANTHEMUM INDICUM/ERIGERON ANNUUS EXTRACT.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

This botanical blend is a multi-functional powerhouse, combining potent antioxidant, anti-inflammatory, and skin-brightening properties. It effectively combats environmental stressors, soothes irritation, and promotes a more uniform, radiant complexion by addressing melanin production and supporting overall skin health.

Summary

Antioxidant Anti-inflammatory Skin Brightening Anti-aging Antimicrobial Soothing

Science

Mechanism of Action

The extract's efficacy primarily stems from the *Chrysanthemum indicum* component, rich in flavonoids like linarin and luteolin. It functions as a potent antioxidant, actively scavenging reactive oxygen species (ROS) and providing defense against damage induced by UV radiation, pollution, and the aging process. Its anti-inflammatory action is demonstrated by inhibiting UV-induced inflammation, reducing inflammatory cytokine production, and decreasing NF-κB, ERK, and p38 MAPK activation. Skin-whitening and anti-melanogenic effects are achieved through the inhibition of tyrosinase activity, leading to a reduction in melanin levels. Additionally, it exhibits antimicrobial properties against various common skin bacteria. The *Erigeron annuus* component contributes complementary anti-fungal, anti-inflammatory, and antioxidant activities, attributed to its diverse profile of coumarins, flavonoids, and terpenoids, collectively protecting, calming, and evening the skin tone.

Research

Clinical Evidence

High confidence
Effective range N/A
Optimal

0.5%

Key findings

  1. 01 Topical application of cosmetic formulations containing 0.5% *Chrysanthemum indicum* water extract significantly reduced melanin levels in human volunteers over 6 weeks.
  2. 02 *Chrysanthemum indicum* extracts demonstrated significant antioxidant activity, with DPPH scavenging IC50 values as low as 1.109 µg/mL for aqueous fractions and 1.350 µg/mL for ethanolic extracts.
  3. 03 Aqueous extracts of *Chrysanthemum indicum* inhibited collagenase activity with an IC50 of 2.33 mg/ml and tyrosinase activity with an IC50 of 102.11 mg/ml.
  4. 04 Aqueous *Chrysanthemum indicum* extract inhibited the growth of common skin bacteria, including *Staphylococcus aureus* and *Pseudomonas aeruginosa*, at minimum inhibitory concentrations (MICs) ranging from 0.025% to 0.1%.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

The *Chrysanthemum indicum* component is water miscible, and its extracts are typically prepared with water or ethanol, indicating good solubility in polar solvents. To maintain optimal antioxidant activity, controlled extraction temperatures (e.g., 40°C during evaporation) are recommended.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has not specifically assessed the combined CHRYSANTHEMUM INDICUM/ERIGERON ANNUUS EXTRACT. However, safety data for *Chrysanthemum indicum* indicates a low risk of toxicity and mutagenicity, with no mortality or clinical signs observed in acute oral toxicity studies up to 2,000 mg/kg body weight/day, and no mutagenicity in bacterial reverse mutation tests up to 500 μg/mL. Its widespread use in traditional medicine and as a food/tea suggests a history of safe topical application.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

A highly versatile botanical ingredient offering significant antioxidant, anti-inflammatory, and brightening benefits, making it a valuable addition for a broad range of precision skincare applications.

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