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Moumoujus

CHRYSANTHELLUM AMERICANUM EXTRACT.

Valuable CAS 94166-95-7 / SKIN CONDITIONING

Chrysanthellum Americanum Extract is a plant-derived ingredient rich in bioactive compounds like flavonoids and saponins. It is recognized for its potent antioxidant and anti-inflammatory properties, playing a key role in supporting healthy skin microcirculation and fortifying capillary walls.

Summary

Antioxidant Anti-inflammatory Microcirculation Support Skin Conditioning Collagen Production Support Vascular Strengthening

Science

Mechanism of Action

This extract operates through a multifaceted biological pathway on the skin. Its high concentration of flavonoids, saponins, and phenolic compounds confers potent antioxidant activity, neutralizing free radicals that contribute to skin aging. Concurrently, it exerts anti-inflammatory action by inhibiting 5-lipoxygenase and reducing leukotriene production. Crucially, it enhances microcirculation by increasing capillary permeability, positively influencing vascular wall integrity, and exhibiting venotonic properties via compounds like chrysanthellin A and B. Furthermore, it aids in tissue repair and aging prevention by promoting collagen synthesis and reducing the fragility and permeability of small vessels.

Research

Clinical Evidence

Medium confidence
Effective range 1–10%
Optimal

N/A

Key findings

  1. 01 Cosmetic and dermatological compositions containing 1% to 10% by weight of dry Chrysanthellum Americanum extract demonstrated anti-inflammatory action and effective regulation of cutaneous microcirculation. (Source: FR-A-2,618,071)
  2. 02 Topical compositions utilizing 0.01% to 2% of dry Chrysanthellum Indicum extract (a related species, corresponding to 0.5% to 1% of a 2% solution) exhibited a significant anti-inflammatory effect. (Source: EP1521586B1)

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Conflicts

  • Individuals with allergies to plants of the Asteraceae family due to sesquiterpene lactones.

Safety

Safety Profile

CIR Status
Not reviewed
Sensitization risk Moderate

The Cosmetic Ingredient Review (CIR) has not conducted a specific safety assessment. While the FDA lists it as a cosmetic ingredient for skin conditioning, its various toxicity levels (oral, parenteral, dermal, inhalation) are undetermined. The ingredient contains sesquiterpene lactones, which necessitates caution for individuals with known allergies to plants of the Asteraceae (daisy) family. Although generally considered non-irritating by some sources, there is a noted likelihood of irritation, especially when formulated with other potentially problematic ingredients.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

This extract is a valuable addition to skincare formulations, effectively targeting inflammation, oxidative stress, and microcirculatory concerns, particularly beneficial for sensitive and vascularly compromised skin.

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