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Moumoujus

CHLOROPHYLLIN-COPPER COMPLEX.

Valuable CAS 11006-34-1 / ANTIOXIDANT, COLORANT, DEODORANT

Chlorophyllin-Copper Complex is a stable, water-soluble derivative of chlorophyll, recognized for its potent antioxidant and anti-inflammatory capabilities. It actively supports the skin's natural repair processes and regeneration, making it a versatile ingredient for addressing signs of aging, photodamage, and blemishes. This complex also exhibits antimicrobial and deodorizing properties, contributing to overall skin health and clarity.

Summary

Antioxidant Anti-inflammatory Skin Regenerative Antimicrobial Wound Healing Deodorant Cosmetic Colorant

Science

Mechanism of Action

This ingredient functions primarily as a powerful antioxidant, effectively neutralizing free radicals and mitigating oxidative stress within skin cells. It possesses anti-inflammatory properties that help to soothe irritated skin and minimize visible redness. Chlorophyllin-Copper Complex supports cellular renewal and skin regeneration, stimulating the production of new, healthy cells for a more vibrant complexion. Its antimicrobial and growth-inhibiting actions are beneficial for preventing microorganism growth, aiding in breakout management, and combating skin infections. Additionally, it offers a deodorizing effect by binding with odor-causing compounds on the skin's surface, promotes wound healing, and may regulate hyaluronic acid levels by inhibiting hyaluronidase activity.

Research

Clinical Evidence

High confidence
Effective range 0.05–0.1%
Optimal

N/A

Key findings

  1. 01 Topical treatment with a liposomal dispersion of 0.05% sodium copper chlorophyllin yielded a statistically significant improvement in the repair of photoaged skin over 12 days. This was achieved by stimulating biomarkers of dermal repair, including procollagen 1, fibrillin 1, and epidermal and dermal mucins. Furthermore, it proved clinically effective and well-tolerated for mild-to-moderate photodamage and solar lentigines over an 8-week period.
  2. 02 A topical gel formulated with 0.066% chlorophyllin complex salts was clinically effective and well-tolerated for treating mild-to-moderate photodamage and solar lentigines over 8 weeks, demonstrating statistically significant improvements in key efficacy parameters.
  3. 03 A topical formulation containing a liposomal dispersion of 0.1% sodium copper chlorophyllin complex showed clinical efficacy and good tolerability over 3 weeks for managing mild-to-moderate acne and reducing the appearance of large, visible pores.

Transparency

Dusting Analysis

Not commonly dusted

The Formula

Formulation

Solubility
Water
Optimal pH N/A
0 7 14

Stability

Sodium Copper Chlorophyllin is a water-soluble derivative known for its enhanced stability. Compared to plain chlorophylls, the replacement of magnesium with copper makes it more resistant to degradation by light and heat. It can be readily incorporated into diverse formulations, including tablets, capsules, powders, liquids, creams, and lotions.

Safety

Safety Profile

CIR Status
Deferred evaluation
Sensitization risk Low

The Cosmetic Ingredient Review (CIR) has deferred evaluation of Chlorophyllin-Copper Complex due to prior safety assessment by the FDA. The FDA has approved it as a color additive exempt from certification for cosmetic use, including dentifrices up to 0.1%. In the European Union, it is recognized as CI 75810 and is permissible as a coloring agent in all cosmetic and personal care products. While generally well-tolerated topically, it is important to note that the European Food Safety Authority (EFSA) has indicated a need for more contemporary safety data for its use as a food additive (E141) to establish a firm opinion, as critical toxicological studies date back to the 1950s.

Your Skin

Skin Compatibility

Yes Normal
No Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Verdict

Valuable

Chlorophyllin-Copper Complex is a valuable ingredient, clinically proven to enhance photoaged skin repair, reduce photodamage, treat mild-to-moderate acne, and minimize pore appearance, while providing robust antioxidant and anti-inflammatory support with low irritancy.

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