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CHITOSAN ARGININAMIDE.

Valuable / ANTIPLAQUE, CLEANSING, SURFACTANT - CLEANSING

A high-performance cationic bio-polymer engineered by grafting the amino acid Arginine onto a Chitosan backbone to enhance solubility and biocompatibility. This multifunctional ingredient serves as both a sophisticated cleansing agent and a protective film-former, providing microbial defense while maintaining the integrity of the skin's moisture barrier.

skin conditioning biocompatible surfactant antimicrobial agent film-forming protector molecular cleansing

Science

Operating as a 'molecular magnet,' this positively charged (cationic) polymer electrostatically binds to the negatively charged surfaces of skin cells and bacterial cell walls. This attraction allows it to effectively lift away debris and environmental pollutants during cleansing while simultaneously depositing a breathable, protective lattice that locks in hydration and physically disrupts pathogenic bacterial membranes.


Research

High confidence
Effective range 0.05–5%
Optimal

0.2%

Key findings

  1. 01 Concentrations as low as 0.2% have been identified as the Minimum Inhibitory Concentration (MIC) for disrupting biofilm and bacterial accumulation.
  2. 02 Ophthalmic studies at 0.5-5.0% confirm exceptional mucosal tolerance and the ability to facilitate sustained active ingredient delivery without irritation.
  3. 03 Clinical applications at 0.05% demonstrate significant efficacy in debris removal and tissue health maintenance in sensitive mucosal environments.

Transparency

Not commonly dusted
Min. effective
0.05%
Red flag below
0.01%

Because Chitosan Argininamide is bioactive at extremely low levels (0.05%), it is rarely 'dusted' in the traditional sense; however, formulations using it below 0.05% likely fail to leverage its antimicrobial and film-forming benefits.


The Formula

Solubility
Water
Optimal pH 4 – 9
0 7 14

Stability

Exhibits superior stability compared to standard Chitosan, remaining effective and stable at physiological skin pH (5.5) and up to alkaline environments of pH 9.0.

Synergies

  • Hyaluronan
  • Non-ionic surfactants
  • Glycerin

Conflicts

  • Anionic surfactants
  • Carbomers
  • Sodium Lauryl Sulfate (SLS)
  • Highly anionic polymers

Safety

CIR Status
Safe as used
Max tested
18%
Pregnancy
Safe
Sensitization risk Low

Safety is supported by the biocompatibility of its parent components; Arginine is CIR-cleared up to 18% in leave-on products, and Chitosan is widely recognized for its non-toxic, biodegradable profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional biotech ingredient for precision cleansing and barrier support, particularly favored for sensitive or compromised skin due to its non-irritating antimicrobial properties.


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