Get a Free 5ml Mini Now Free 5ml Mini With Every Order of The Mantle

CHIMAPHILA UMBELLATA LEAF EXTRACT.

Valuable CAS 89997-56-8 / SKIN CONDITIONING

Commonly known as Pipsissewa, this botanical extract serves as a multi-dimensional skin refiner that balances sebum while addressing oxidative stress. It is particularly valued in precision skincare for its ability to provide a sensory cooling effect alongside its biological brightening properties.

Skin Conditioning Antioxidant Antimicrobial Soothing Astringent

Science

This extract utilizes a diverse phytochemical profile to enhance skin health: Chimaphilin provides targeted antimicrobial action, while natural arbutin precursors inhibit tyrosinase to modulate melanin production. Additionally, high concentrations of tannins provide an astringent effect, and its interaction with TRPM8 receptors induces a refreshing, cooling sensation upon application.


Research

Medium confidence
Effective range 0.07–1%
Optimal

0.5%

Key findings

  1. 01 Demonstrated potent antifungal efficacy against Malassezia globosa, making it effective for scalp and barrier health.
  2. 02 Significant inhibition of LDH-A enzymes, indicating a high potential for calming inflammatory skin responses.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its potency in small concentrations and status as a 'natural' extract, it is frequently used at trace levels (<0.01%) for marketing claims. For therapeutic antifungal or brightening benefits, concentrations should ideally exceed 0.1%.


The Formula

Solubility
Both
Optimal pH 4 – 9
0 7 14

Stability

Highly sensitive to metal ions; the presence of iron or ferric salts will trigger a chemical reaction resulting in a pink or reddish discoloration of the finished formula.

Synergies

  • Vitamin C
  • Niacinamide
  • Soothing Polysaccharides

Conflicts

  • Iron salts
  • Ferric compounds

Safety

CIR Status
Not reviewed
Max tested
1%
Pregnancy
Safe
Sensitization risk Low

While not formally reviewed by the CIR, it has a long history of safe use in topical cosmetics with no reported FDA restrictions.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Unknown
Comedogenicity Unknown

Our Assessment

Valuable

A versatile botanical active that bridges the gap between antimicrobial protection and skin brightening, provided it is formulated away from iron salts.


Related

Finding similar ingredients…