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Moumoujus

CETYL PCA.

Valuable CAS 37673-20-4 / SKIN CONDITIONING

A sophisticated lipid-ester that merges the hydrating power of Pyrrolidone Carboxylic Acid (PCA) with the emollient properties of Cetyl alcohol. This bio-mimetic ingredient is designed to reinforce the skin's natural lipid barrier while providing a smooth, non-greasy finish.

Summary

Emollient Skin-Conditioning Agent Barrier Repair Humectant

Science

Mechanism of Action

It functions as a lipophilic delivery system for PCA, a key component of the skin's Natural Moisturizing Factor (NMF). By integrating into the intercellular lipid matrix, it prevents trans-epidermal water loss (TEWL) and maintains the structural integrity of the stratum corneum.

Research

Clinical Evidence

High confidence
Effective range 0.5–5%
Optimal

2%

Key findings

  1. 01 Evaluation of NMF-precursors in barrier repair
  2. 02 Lipid-ester penetration and emolliency profiles

Transparency

Dusting Analysis

Not commonly dusted
Min. effective
0.2%
Red flag below
0.1%

Because it functions as an emollient and barrier-repair agent, inclusion levels below 0.5% are generally insufficient to provide measurable physiological benefits to the lipid bilayer.

The Formula

Formulation

Solubility
Oil
Optimal pH 4 – 7.5
0 7 14

Stability

Highly stable in O/W and W/O emulsions; resistant to oxidation compared to unsaturated fatty acids.

Synergies

  • Ceramides
  • Cholesterol
  • Glycerin

Safety

Safety Profile

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Non-irritating and non-sensitizing even in high-purity clinical trials.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An excellent choice for precision barrier repair, offering the hydration of NMFs with the protective qualities of a lipid-soluble emollient.

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