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CETYL 3-GLYCERYL ASCORBATE.

Essential / ANTIOXIDANT, HUMECTANT

An advanced, amphiphilic Vitamin C derivative that fuses L-ascorbic acid with a moisturizing glyceryl group and a lipophilic cetyl chain. This engineered molecular structure ensures deep epidermal penetration and exceptional oxidative stability without the acidity-induced irritation of traditional Vitamin C.

Antioxidant Humectant Skin-conditioning Brightening agent Collagen synthesis promoter

Science

This lipophilic molecule integrates seamlessly into the skin's cellular phospholipid bilayers, where it serves as a sustained-release antioxidant. It functions as a crucial cofactor for hydroxylase enzymes to stabilize collagen fibers while simultaneously inhibiting tyrosinase activity to modulate melanin production and transport.


Research

High confidence
Effective range 0.1–1.25%
Optimal

1%

Key findings

  1. 01 Topical application at 1.0–1.25% twice daily demonstrated a significant improvement in skin texture and epidermal uptake over 4 weeks (Cosmetics 2021).
  2. 02 In vitro data confirms that concentrations as low as 0.1% effectively promote collagen synthesis and suppress melanogenesis by inhibiting tyrosinase and melanin transport.

Transparency

Not commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Because this is a specialty 'iVC' derivative, it is frequently used at active levels (0.5–1.0%). However, claims of 'Vitamin C' benefits in products containing less than 0.1% are likely marketing-driven ('dusting') and may not provide meaningful collagen or brightening support.


The Formula

Solubility
Both
Optimal pH 3 – 6
0 7 14

Stability

Highly resistant to oxidation; unlike pure Vitamin C, it remains stable in a broad pH range and does not require a highly acidic environment (pH <3.5) for efficacy.

Synergies

  • Tocopherol
  • Ferulic Acid
  • Glycerin
  • Broad-spectrum Sunscreen

Conflicts

  • Strong oxidizing agents
  • Heavy metal ions (Iron, Copper)
  • Extended exposure to temperatures above 40°C

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Classified under the safe 'Ethers and Esters of Ascorbic Acid' category. It is non-carcinogenic and formulated to be non-irritating even for reactive skin types.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Essential

A high-performance, precision Vitamin C derivative that offers the clinical benefits of collagen support and brightening with superior stability and low irritation potential.


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