Science
Mechanism of Action
This ingredient operates via a dual-action pathway: it forms an invisible, cohesive biological film on the stratum corneum for immediate mechanical tightening, while simultaneously acting as an autophagy activator. By stimulating the skin's internal recycling system and enhancing ceramide synthesis, it optimizes cellular detoxification and reinforces the lipid barrier.
Research
Clinical Evidence
High confidence2%
Key findings
- 01 Clinical trials on Aquatide-based formulations demonstrate significant measurable improvements in skin elasticity and dermal moisture retention over a 4 to 8-week period.
- 02 In vivo evaluations confirm a temporary mechanical lifting effect upon application due to the formation of a structured peptide matrix.
Transparency
Dusting Analysis
Due to its high manufacturing cost as a specialized peptide polymer, it is often included at sub-clinical levels (below 1%) purely for marketing claims. Efficacy for lifting and autophagy activation requires a concentration of at least 1%.
The Formula
Formulation
Stability
Highly stable in water-based systems within a physiological pH range, but prone to degradation if exposed to extreme thermal stress or highly acidic/alkaline environments.
Synergies
- Ceramides
- Hyaluronic Acid
- Other Autophagy-inducing Peptides
Conflicts
- Strong oxidizing agents
- Cationic surfactants
- Low pH exfoliating acids
Safety
Safety Profile
While not yet formally reviewed by the CIR, its structural similarity to other polyaspartic acid derivatives and established peptide safety profiles suggests it is non-irritating and safe for cosmetic use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An exceptional multi-functional peptide for precision aging protocols, offering both immediate structural lifting and long-term cellular health benefits.
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References
Sources