Science
Mechanism of Action
This ingredient utilizes secondary metabolites known as CLEPS to upregulate filaggrin expression, which reinforces the physical skin barrier. It simultaneously boosts Type I collagen synthesis while providing a 93.4% inhibition of collagenase (MMP-1) to prevent matrix degradation, and suppresses melanin pathways via tyrosinase inhibition.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 In-vitro analysis demonstrated a 65.4% increase in collagen synthesis and a 36% rise in filaggrin production.
- 02 Significant reduction of inflammatory markers (NO, iNOS, and TNFα) observed at concentrations between 100-500 µg/mL.
- 03 Proven enzymatic inhibition of collagenase by 93.4%, effectively shielding the dermal matrix from environmental aging factors.
Transparency
Dusting Analysis
Because it shows anti-inflammatory activity at very low concentrations (0.01%), it is rarely 'dusted' in a way that renders it useless, though higher concentrations are necessary for the 65%+ collagen synthesis boost.
The Formula
Formulation
Stability
Highly stable secondary metabolite; heat-resistant and maintains biological activity for 12-24 months under standard conditions.
Synergies
- Peptides
- Niacinamide
- Hyaluronic Acid
- Vitamin C
Safety
Safety Profile
Maintains an EWG Green Level 1 rating with zero reported cytotoxicity in human dermal fibroblasts even at high concentrations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A versatile and potent bio-ferment that exceptionally targets the three pillars of skin health: barrier strength, collagen density, and pigment uniformity.
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References
Sources