Science
Mechanism of Action
This ceramide functions by integrating into the intercellular lipid matrix of the stratum corneum, forming dense, highly organized structures. These structures create a robust, yet selectively permeable, protective barrier. This enhanced impermeability safeguards the skin from desiccation, contaminants, and irritants, while contributing to long-term barrier resilience and defending against UV-induced damage by preventing excessive moisture loss or over-hydration. Adequate ceramide levels are crucial for a strong, healthy skin barrier.
Research
Clinical Evidence
High confidenceN/A
Key findings
- 01 A ceramide-containing product, with ceramides at 0.5% (5000 ppm), notably improved skin absorption parameters (amount, depth, speed) in individuals with dry skin compared to non-ceramide controls.
- 02 Ceramide usage rates typically range from 0.5% to 5%, though efficacy isn't solely proportional to higher percentages, as ceramides function optimally within structured delivery systems.
- 03 A ceramide-enriched moisturizing cream significantly increased skin hydration and immediately reduced visible dry skin signs and discomfort, with stratum corneum ceramide, cholesterol, and free fatty acid levels increasing substantially after 4 weeks.
Transparency
Dusting Analysis
Ceramides, including Ceramide NG Dilaurate, are recognized as fundamental skin-identical ingredients essential for barrier integrity and moisture. While their efficacy is significantly influenced by structured delivery systems, using them in formulations is a standard practice for genuine skin benefits, not for 'dusting' or marketing without substance. Therefore, its presence is generally a positive indicator, though formulation quality impacts overall effectiveness.
The Formula
Formulation
Stability
Ceramide NG Dilaurate is lipophilic and should be incorporated into the oil phase of emulsions before emulsification, ideally dispersed in lipids or oils. It maintains stability within a pH range of 4.5 to 6.5, but extreme pH environments can compromise its structural integrity. Due to its inherent low solubility in both water and oil, and a tendency to recrystallize, stable incorporation can be challenging. Utilizing a nonionic surfactant (HLB 9-20) alongside a liquid polyhydric alcohol can aid solubilization. As ceramides are generally heat-sensitive, addition to formulations should occur at temperatures of 40°C or below.
Synergies
- Cholesterol
- Free fatty acids
- Nonionic surfactants (HLB 9-20)
- Liquid polyhydric alcohols
Conflicts
- Highly acidic environments
- Highly alkaline environments
Safety
Safety Profile
The CIR Expert Panel determined ceramide ingredients, including Ceramide NG (formerly Ceramide 2) and Ceramide NS Dilaurate, to be 'safe in cosmetics in the present practices of use and concentration'. While no specific maximum concentration for Ceramide NG Dilaurate was explicitly reported, a maximum use of 0.2% was noted for Ceramide NG (Ceramide 2) in eye lotions and face/neck skincare preparations. No SCCS or explicit FDA approval was found; however, the FDA's Voluntary Cosmetic Registration Program (VCRP) tracks ceramide usage.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Ceramide NG Dilaurate is an essential skin-identical ingredient that significantly contributes to a strong, hydrated, and resilient skin barrier across all skin types.
Related
Similar Ingredients
Finding similar ingredients…