Science
Mechanism of Action
Centipeda Cunninghamii Leaf/Stem Extract operates by actively counteracting inflammatory pathways, specifically inhibiting markers such as PGE2, COX, NO, and TNF-α. Its rich composition of phenolics, flavonoids, terpenoids, and chlorogenic acids provides substantial antioxidant defense, safeguarding skin cells from free radical damage and environmental oxidative stress, which contribute to premature aging. The extract further stimulates cellular regeneration and collagen synthesis, leading to improved skin elasticity and a reduction in the appearance of fine lines. Additionally, it possesses antimicrobial properties to help prevent infections, offers anti-allergenic protection, and contributes to sebum regulation.
Research
Clinical Evidence
Medium confidenceN/A
Key findings
- 01 Clinical investigations have demonstrated its ability to minimize inflammation, promote cellular regeneration, and reduce the appearance of fine lines and wrinkles. It is effective in treating itching and dry skin associated with psoriasis, and exhibits proven anti-inflammatory, anti-allergenic, and antioxidant activities, deemed safe and non-irritant for topical application.
Transparency
Dusting Analysis
The Formula
Formulation
Stability
A 50% aqueous ethanol extract demonstrates optimal stability within a pH range of 5.1 to 5.5. To enhance storage stability and prevent the precipitation of slightly soluble compounds like phlobaphenes, glycerol can be incorporated, also acting as a preservative.
Safety
Safety Profile
Clinically proven to be safe, non-irritant, and non-toxic for topical skincare applications. While traditional usage suggests potential toxicity with large oral ingestion, this does not pertain to dermal application. Dermal toxicity information is not universally determined across all safety references.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Centipeda Cunninghamii Leaf/Stem Extract is a valuable botanical ingredient, offering comprehensive benefits from calming inflammation and protecting against oxidative stress to promoting regeneration and reducing signs of aging, making it suitable for all skin types.
Related
Similar Ingredients
Finding similar ingredients…