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CENTIPEDA CUNNINGHAMII LEAF/STEM EXTRACT.

Valuable / ANTI-SEBUM, ANTIOXIDANT, SKIN PROTECTING

An extract derived from the Centipeda Cunninghamii plant, this ingredient is a potent multi-tasker known for its extensive benefits across skin health. It actively reduces inflammation and oxidative stress, while promoting skin repair and regeneration to address various skin concerns.

antioxidant anti-inflammatory skin-soothing wound healing anti-aging cell regeneration collagen booster antimicrobial anti-allergenic sebum control skin protectant

Science

Centipeda Cunninghamii Leaf/Stem Extract operates by actively counteracting inflammatory pathways, specifically inhibiting markers such as PGE2, COX, NO, and TNF-α. Its rich composition of phenolics, flavonoids, terpenoids, and chlorogenic acids provides substantial antioxidant defense, safeguarding skin cells from free radical damage and environmental oxidative stress, which contribute to premature aging. The extract further stimulates cellular regeneration and collagen synthesis, leading to improved skin elasticity and a reduction in the appearance of fine lines. Additionally, it possesses antimicrobial properties to help prevent infections, offers anti-allergenic protection, and contributes to sebum regulation.


Research

Medium confidence
Effective range N/A
Optimal

N/A

Key findings

  1. 01 Clinical investigations have demonstrated its ability to minimize inflammation, promote cellular regeneration, and reduce the appearance of fine lines and wrinkles. It is effective in treating itching and dry skin associated with psoriasis, and exhibits proven anti-inflammatory, anti-allergenic, and antioxidant activities, deemed safe and non-irritant for topical application.

Transparency

Not commonly dusted

The Formula

Solubility
Both
Optimal pH 5.1 – 5.5
0 7 14

Stability

A 50% aqueous ethanol extract demonstrates optimal stability within a pH range of 5.1 to 5.5. To enhance storage stability and prevent the precipitation of slightly soluble compounds like phlobaphenes, glycerol can be incorporated, also acting as a preservative.


Safety

CIR Status
Not reviewed
Sensitization risk Low

Clinically proven to be safe, non-irritant, and non-toxic for topical skincare applications. While traditional usage suggests potential toxicity with large oral ingestion, this does not pertain to dermal application. Dermal toxicity information is not universally determined across all safety references.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Unknown

Our Assessment

Valuable

Centipeda Cunninghamii Leaf/Stem Extract is a valuable botanical ingredient, offering comprehensive benefits from calming inflammation and protecting against oxidative stress to promoting regeneration and reducing signs of aging, making it suitable for all skin types.


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