Science
Mechanism of Action
Centella Asiatica Meristem Cell Culture Extract functions as an active antioxidant, mitigating oxidative stress by inhibiting oxygen-promoted reactions and thereby preserving cellular integrity and product stability. It concurrently serves as a robust skin-protecting agent, shielding the skin from external environmental aggressors. Mechanistically, this extract is known to significantly promote fibroblast proliferation and increase the biosynthesis of collagen, specifically Type I and III, alongside intracellular fibronectin. This activity contributes to improved tensile strength in newly formed skin and aids in the modulation of inflammatory phases associated with hypertrophic scars and keloids. Further benefits include enhanced tissue regeneration, accelerated cell migration, and optimized wound healing. The extract also boosts hyaluronic acid synthesis, which enhances skin hydration and barrier function, improves microcirculation, and provides broad protection against environmental damage. Its inherent anti-inflammatory and antibacterial properties make it particularly beneficial for managing acne-prone and sensitive skin conditions.
Research
Clinical Evidence
Insufficient-data confidenceN/A
Transparency
Dusting Analysis
The Formula
Formulation
Stability
A pH range of 4.5-7.5 is advised for optimal stability, consistent with similar Centella asiatica cell culture extracts. General Centella asiatica extracts have shown minimal pH variation in accelerated stability tests.
Safety
Safety Profile
The Cosmetic Ingredient Review (CIR) Expert Panel has concluded that Centella Asiatica Meristem Cell Culture and its extract are safe for use in cosmetics within established practices and concentrations, provided formulations are designed to be non-sensitizing. Notably, a raw material containing 20% Centella asiatica cells in 80% glycerol demonstrated non-irritant properties in ocular irritation evaluations.
Your Skin
Skin Compatibility
Our Assessment
Verdict
Centella Asiatica Meristem Cell Culture Extract is a valuable, multi-functional ingredient providing significant antioxidant, protective, and regenerative benefits, suitable for all skin types due to its robust safety profile and broad spectrum of action.
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