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CATALPA OVATA FRUIT EXTRACT.

Valuable / SKIN CONDITIONING

A potent botanical bioactive derived from the Yellow Catalpa tree, utilized for its dual ability to suppress inflammatory pathways and inhibit melanin synthesis. This extract provides a sophisticated approach to brightening and calming the skin barrier simultaneously.

Soothing Antioxidant Skin Brightening Anti-inflammatory

Science

The extract utilizes iridoid glycosides like catalposide to inhibit the production of nitric oxide and pro-inflammatory cytokines (IL-1β, IL-6). For pigmentation, it modulates the cAMP/CREB signaling pathway, which effectively downregulates tyrosinase activity to prevent melanin overproduction.


Research

Medium confidence
Effective range 0.01–6%
Optimal

2%

Key findings

  1. 01 Inhibition of iNOS and Nitric Oxide production at 0.1 mg/mL (Planta Medica, 2002)
  2. 02 Inhibition of alpha-MSH-induced melanogenesis via the cAMP/CREB pathway (NIH/MDPI, 2023)

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Due to its efficacy at low concentrations (0.1 mg/mL) in lab settings, brands often include it at trace levels for label claims without providing sufficient levels for melanogenesis inhibition.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Optimal stability is maintained in aqueous or hydro-glycolic bases; avoid extreme heat during the cool-down phase to preserve glycoside integrity.

Synergies

  • Niacinamide
  • Vitamin C
  • Tranexamic Acid

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Listed as a safe skin-conditioning agent in EU and FDA databases; shows low toxicological risk profile.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-precision botanical that addresses both hyperpigmentation and chronic micro-inflammation.


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References