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CASSIA ITALICA LEAF POWDER.

Valuable CAS 85085-71-8 / SKIN CONDITIONING

A nutrient-dense botanical powder derived from the leaves of the Senna italica plant, commonly known as 'neutral henna.' It serves as a multifunctional bioactive agent that delivers intense antioxidant protection while actively calming inflammatory skin responses.

Antioxidant Skin Conditioning Soothing Agent Antimicrobial

Science

The powder functions through a high concentration of flavonoids and tannins which neutralize free radicals and fortify the skin's moisture barrier. Its specific anti-inflammatory pathway involves chrysophanic acid and sennosides, which inhibit prostaglandin release to reduce visible irritation, while its unique protein-complexing ability provides targeted antimicrobial defense against common skin pathogens like S. aureus.


Research

Medium confidence
Effective range 1–100%
Optimal

100%

Key findings

  1. 01 A 2021 Spanish pilot study demonstrated that a 100% paste application reduced erythema and pruritus in 70% of subjects over a 14-day period.
  2. 02 In vivo pharmacological models confirmed significant antipyretic and anti-inflammatory activity, showing measurable reductions in localized swelling.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.5%

Because it is often marketed as 'neutral henna' in hair care, brands frequently include it at negligible percentages (below 0.5%) for label claims. To achieve the documented soothing benefits for the skin, higher concentrations or concentrated extracts are required.


The Formula

Solubility
Water
Optimal pH 4.5 – 7
0 7 14

Stability

Highly stable in dry powder form; however, aqueous mixtures are prone to oxidation and should be prepared fresh. Liquid extracts require a slightly acidic environment for maximum longevity.

Synergies

  • Humectants
  • Soothing botanicals
  • Acidic stabilizers

Conflicts

  • Strong oxidizing agents
  • Metal ions/utensils (due to tannin reactivity)
  • High pH environments

Safety

CIR Status
Not reviewed
Max tested
100%
Pregnancy
Safe
Sensitization risk Low

Classified as SkinSafe 100, making it an excellent candidate for reactive skin types. It carries no regulatory penalties in European cosmetic databases (COSMILE).


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally safe, non-irritating botanical that offers proven relief for redness and oxidative stress, particularly effective in mask or paste formulations.


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References