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CASSIA ANGUSTIFOLIA LEAF EXTRACT.

Valuable CAS 85187-05-9 / SKIN CONDITIONING

A high-performance botanical humectant derived from the Senna plant, often recognized as a natural alternative to hyaluronic acid. It excels at creating a moisture-locking breathable film while providing secondary antioxidant benefits to support the skin barrier.

Humectant Skin Conditioning Agent Film Former Antioxidant

Science

The extract utilizes a high concentration of polysaccharides to form a protective, hydrating film on the stratum corneum that significantly reduces trans-epidermal water loss. Beyond surface hydration, its flavonoid content (rutin and kaempferol) neutralizes oxidative stress, while sennosides contribute to a calmed, anti-inflammatory skin environment.


Research

High confidence
Effective range 0.003–5%
Optimal

1%

Key findings

  1. 01 In vivo testing demonstrated that even at 0.003%, the extract modulates inflammatory responses and accelerates wound healing by priming adipose-derived stem cells.
  2. 02 In vitro research indicates that concentrations between 0.0125% and 0.1% effectively inhibit nitric oxide production and boost angiogenesis cytokines in macrophage cells.

Transparency

Commonly dusted
Min. effective
1%
Red flag below
0.1%

While clinical markers for wound healing are seen at very low concentrations, the characteristic 'botanical hyaluronic acid' film-forming effect typically requires 1-5%. Formulas listing this ingredient at the bottom of the deck (below 0.1%) are likely using it for label claims rather than functional hydration.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Highly stable in aqueous systems; however, prolonged exposure to high heat or extreme pH can cause sennosides to degrade into rhein, though this rarely compromises the primary moisturizing efficacy.

Synergies

  • Glycerin
  • Hyaluronic Acid
  • Niacinamide

Conflicts

  • Strong oxidizing agents
  • Highly alkaline environments (pH > 9.0)

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Recognized as FDA GRAS for internal use; topical safety is well-regarded in the industry despite a lack of a formal CIR final monograph.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptional plant-based hydrator that provides immediate surface smoothing and long-term anti-inflammatory support.


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References