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Moumoujus

CASEIN EXTRACT.

Valuable / HAIR CONDITIONING, SKIN CONDITIONING

A sophisticated bovine-derived phosphoprotein complex that functions as a biomimetic skin conditioner. It serves as a superior hydration anchor, forming a protective, nutrient-dense film that reinforces the dermal barrier while providing essential amino acid precursors.

Summary

Skin-conditioning Humectant Film-forming Antistatic Barrier support

Science

Mechanism of Action

Casein extract operates via a dual-action 'eutrophic' mechanism: it forms a breathable, water-rich film over the stratum corneum to dramatically reduce trans-epidermal water loss (TEWL) while simultaneously delivering amino acids that replenish the skin's Natural Moisturizing Factor (NMF). This helps stabilize the skin's moisture balance and provides an immediate smoothing, antistatic effect.

Research

Clinical Evidence

High confidence
Effective range 0.1–2%
Optimal

2%

Key findings

  1. 01 Concentrations of 2% in leave-on applications demonstrate significant improvements in skin conditioning and a measurable reduction in TEWL.
  2. 02 Human Repeated Insult Patch Tests (HRIPT) at 30% concentration confirmed no evidence of dermal irritation, establishing a high safety ceiling.
  3. 03 Formulations at 0.1% are clinically utilized to provide immediate tactile smoothing and barrier support in targeted neck and face treatments.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

While 0.1% provides surface-level smoothing, concentrations below 0.5% in leave-on products are often used for marketing claims rather than biological barrier repair. Effective clinical results for moisture retention are typically observed at the 2% threshold.

The Formula

Formulation

Solubility
Water
Optimal pH 5.5 – 8
0 7 14

Stability

Highly sensitive to its isoelectric point (~pH 4.6); acidification below pH 4.5 will cause the protein to precipitate. Stability is maximized in neutral to slightly alkaline environments.

Synergies

  • Hyaluronic Acid
  • Glycerin
  • Ceramides

Conflicts

  • Strong Alpha Hydroxy Acids (AHAs)
  • High electrolyte concentrations (salting out risk)
  • Excessive thermal processing (denaturation)

Safety

Safety Profile

CIR Status
Safe as used
Max tested
2%
Pregnancy
Safe
Sensitization risk Low

Although a food allergen, topical application has shown no evidence of Type I hypersensitivity. It is considered safe for leave-on cosmetic use up to 2%.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional biocompatible film-former that provides both immediate smoothing and long-term barrier replenishment when formulated at therapeutic levels.

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