Science
Mechanism of Action
This extract functions as a genomic activator for skin density by upregulating the expression of tropoelastin and lysyl oxidase (LOX), the enzyme essential for cross-linking elastin fibers. Beyond synthesis, it provides protective coverage by inhibiting elastase—the enzyme responsible for fiber breakdown—and modulates the inflammatory cascade by suppressing Phospholipase A2 (PLA2) and neutralizing free radicals through enhanced Superoxide Dismutase (SOD) activity.
Research
Clinical Evidence
High confidence2.5%
Key findings
- 01 In vitro gene expression analysis (US Patent 2016/0220476 A1) demonstrating significant increases in tropoelastin and LOX production.
- 02 Histological parameters study (2022) showing improved angiogenesis and capillary permeability for accelerated skin reorganization.
- 03 Pharmacological evaluation (2022) confirming systemic antioxidant effects via lipid peroxidation reduction.
Transparency
Dusting Analysis
While gene expression can be influenced at very low levels, the therapeutic benefits for firming and post-procedure recovery typically require concentrations above 0.05%. It is frequently used in 'label-only' capacities in mass-market botanical blends.
The Formula
Formulation
Stability
Highly resilient to thermal processing (stable up to 121°C). It maintains its terpenoid and phenolic integrity best when protected from strong oxidizing agents in aqueous or emulsion systems.
Synergies
- Retinoids
- Vitamin C
- Copper Peptides
Conflicts
- Strong oxidizing agents
Safety
Safety Profile
Recognized for its high safety margin with a long history of traditional use; non-toxic in pre-clinical models up to 2000 mg/kg.
Your Skin
Skin Compatibility
Our Assessment
Verdict
An exceptional precision botanical that offers rare genetic support for elastin architecture and rapid soothing for compromised skin barriers.
Related
Similar Ingredients
Finding similar ingredients…
References
Sources