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CARTHAMUS TINCTORIUS LEAF EXTRACT.

Valuable CAS 223749-52-8 (generic) / ANTIOXIDANT, UV FILTER

A botanical antioxidant derived from the leaves of the Safflower plant, valued for its high concentration of defensive polyphenols. It provides a multi-functional approach to skincare by soothing inflammation while offering secondary protection against environmental oxidative stress.

antioxidant skin conditioning soothing agent tyrosinase inhibitor mild uv protector

Science

This extract utilizes a high concentration of flavonoids, specifically luteolin, and polyphenols (measured at approximately 7.18 mg GAE/g) to neutralize reactive oxygen species. It functions as a biological shield by inhibiting pro-inflammatory cytokines and suppressing tyrosinase activity, which helps to regulate melanin production and maintain even skin tone.


Research

Medium confidence
Effective range 2–5%
Optimal

3.5%

Key findings

  1. 01 In vitro analysis confirms high reducing power and potent antioxidant capacity with low hemolytic toxicity (3.8%).
  2. 02 Comparative ingredient data suggests a 2-5% range for significant skin-conditioning and defensive benefits.

Transparency

Commonly dusted
Min. effective
2%
Red flag below
0.5%

Many botanical formulations include this extract at levels below 0.5% for marketing claims ('label dusting'). To achieve documented antioxidant and brightening effects, concentrations should ideally reach the 2% threshold.


The Formula

Solubility
Water
Optimal pH 4 – 7
0 7 14

Stability

Aqueous extracts are sensitive to thermal degradation; maintain processing temperatures below 85°C. Storage in light-protected, cool environments is essential to preserve phenolic integrity.

Synergies

  • Vitamin E (Tocopherol)
  • Glycols
  • UV Filters

Conflicts

  • Strong oxidizing agents
  • Excessive heat

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

While the leaf specifically lacks a standalone CIR monograph, it is structurally similar to the seed and flower extracts which are CIR-approved. It maintains a 'no penalty' safety profile in international regulatory databases.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical extract that provides excellent antioxidant support and brightening potential when formulated at active concentrations.


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