Science
Mechanism of Action
This functionalized carbohydrate operates via a dual-action pathway: it creates an occlusive bio-polymeric film that significantly reduces transepidermal water loss (TEWL) and serves as a nanocarrier for unstable actives like growth factors (hEGF). At the cellular level, it promotes the proliferation of fibroblasts and keratinocytes while providing targeted anti-inflammatory and antioxidant defense by neutralizing free radicals.
Research
Clinical Evidence
High confidence5%
Key findings
- 01 Comparative double-blind trials indicate superior wrinkle reduction and hydration metrics when measured against Hyaluronic Acid over a 30-day period.
- 02 At a 1% concentration, the ingredient demonstrates 58% antioxidant activity, effectively mitigating premature aging factors.
- 03 Dermatological testing at 10% concentration confirms the material is non-irritating and highly biocompatible for topical applications.
Transparency
Dusting Analysis
Carboxymethyl Levan is a premium technical ingredient. While antioxidant benefits appear at 1%, its critical role as a nanocarrier and structural film-former requires concentrations above 0.5% to ensure measurable delivery of co-actives.
The Formula
Formulation
Stability
Maintains excellent stability in neutral to alkaline environments; however, it is prone to acid-catalyzed hydrolysis at pH levels below 5.5, which causes the polymer to degrade into fructose.
Synergies
- Human Epidermal Growth Factor (hEGF)
- Hyaluronic Acid
- Peptides
- Glycerin
Conflicts
- Low-pH L-Ascorbic Acid
- Alpha Hydroxy Acids (AHAs)
- Strong oxidizing agents
Safety
Safety Profile
Classified under Microbial Polysaccharide Gums; exhibits zero cytotoxicity or hemolytic activity, making it ideal for sensitive and post-procedure skin.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance polysaccharide that outperforms traditional Hyaluronic Acid in hydration longevity and provides a critical stabilization matrix for advanced bio-actives.
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