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CARAPA GUAIANENSIS SEED OIL.

Valuable CAS 352458-32-3; 906347-26-0 / DENATURANT, SKIN CONDITIONING

Known commonly as Andiroba oil, this Amazonian botanical lipid is prized for its high concentration of limonoids and essential fatty acids. It provides intensive barrier repair while offering unique anti-inflammatory benefits suitable for compromised or reactive skin.

Skin conditioning Emollient Soothing agent Barrier repair

Science

This oil functions through a dual-action pathway: its rich profile of oleic and linoleic acids reinforces the skin's lipid matrix to prevent transepidermal water loss, while bioactive limonoids like andirobin and gedunin modulate inflammatory signaling. Furthermore, it encourages tissue remodeling by prioritizing the synthesis of collagen type III over type I in damaged skin, facilitating smoother recovery.


Research

Medium confidence
Effective range 0.5–10%
Optimal

5%

Key findings

  1. 01 In vitro assays demonstrate that nanoemulsions between 90–360 µg/mL significantly accelerate keratinocyte wound closure by over 50% compared to controls.
  2. 02 Concentrations ranging from 0.5% to 10% have been documented to act as effective anti-irritants that stimulate cutaneous defense mechanisms.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Because it is an exotic oil with high raw material value, it is often 'dusted' at negligible levels (below 0.1%) for marketing claims. A minimum of 0.5% is required for tangible soothing effects, while 2-5% is preferred for barrier restoration.


The Formula

Solubility
Oil
Optimal pH 5.5 – 6.5
0 7 14

Stability

High unsaturated fatty acid content makes it susceptible to rancidity. Stability is significantly improved through nanoemulsification and the inclusion of tocopherols.

Synergies

  • Vitamin E (Tocopherol)
  • Ceramides
  • Squalane

Conflicts

  • Strong oxidizing agents
  • High-heat processing

Safety

CIR Status
Not reviewed
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Recognized as non-toxic with ultra-low dermal toxicity. Industry standards suggest a cap of 10% for leave-on topical applications.


Your Skin

Yes Normal
Yes Dry
No Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical lipid that excels in tissue regeneration and soothing inflammatory pathways, provided it is stabilized with antioxidants.


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