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CAPSICUM ANNUUM CALLUS CULTURE EXTRACT.

Valuable CAS 84625-29-6 / SKIN CONDITIONING

A high-performance biotech 'stem cell' extract derived from red pepper plant tissue, engineered to reinforce the skin's structural integrity without the heat of the fruit. This laboratory-cultivated ingredient delivers a concentrated profile of secondary metabolites that specifically target dermal density and barrier resilience.

Skin Conditioning Antioxidant Skin Protecting Collagen Stimulation

Science

It functions by leveraging bioactive phenolics and flavonoids to activate the skin's internal defense pathways. By inducing a mild tonic effect on microcirculation and up-regulating genes responsible for keratinization, it stimulates collagen synthesis and neutralizes oxidative stress to restructure the cutaneous barrier.


Research

High confidence
Effective range 0.1–3%
Optimal

2%

Key findings

  1. 01 In vivo trials at 1-3% demonstrate measurable improvements in skin structure, visible pore refinement, and the smoothing of fine lines via structural reinforcement.
  2. 02 In vitro data confirms that concentrations as low as 0.1% significantly up-regulate genes involved in cornification, leading to increased dermal density and reduction in periorbital wrinkles.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to the high cost of botanical callus cultures, this ingredient is frequently included at 'label-claim' levels. Formulations must contain at least 0.1% for gene expression benefits and 1% for visible structural improvements.


The Formula

Solubility
Water
Optimal pH 4.5 – 6.5
0 7 14

Stability

Maintains high stability in water-based serums and gels; however, it is thermolabile and should be incorporated during the cool-down phase to prevent degradation of bioactive metabolites.

Synergies

  • Niacinamide
  • Peptides
  • Antioxidants
  • Glycerin

Conflicts

  • Strong oxidizing agents
  • Highly alkaline environments

Safety

CIR Status
Safe as used
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Produced via controlled cell culture, this extract lacks the high concentrations of capsaicinoids found in the fruit, making it significantly less irritating than standard pepper extracts.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An advanced biotechnological active that provides precise structural rejuvenation and antioxidant protection with an excellent safety profile for all skin types.


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