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CAPRYLYL 2-GLYCERYL ASCORBATE.

Valuable CAS 1359731-61-5 / ANTIOXIDANT, HUMECTANT

An advanced, amphiphilic Vitamin C derivative engineered for superior stability and skin penetration. Unlike traditional L-Ascorbic Acid, this molecule is both water and oil-compatible, allowing it to target multiple skin layers to address pigmentation, acne, and aging simultaneously.

Antioxidant Brightening Agent Humectant Anti-Acne Support Collagen Booster

Science

This molecule acts as a multi-stage pigment inhibitor by suppressing tyrosinase activity and blocking melanin transport to the skin's surface. It simultaneously functions as a potent antioxidant to scavenge reactive oxygen species (ROS), stimulates fibroblasts to increase Type I collagen synthesis, and provides antimicrobial benefits against P. acnes while the glyceryl moiety maintains cellular hydration.


Research

High confidence
Effective range 0.01–5%
Optimal

0.1%

Key findings

  1. 01 Clinical trials demonstrated that 0.1% concentration significantly improved post-inflammatory hyperpigmentation (PIH) and metal-allergy induced pigmentation within 1-5 months of twice-daily use.
  2. 02 Studies indicate efficacy as low as 0.01% for reducing acne-related redness and minor pigmentation.
  3. 03 Research shows a reduction in scalp irritation and itching through the inhibition of thromboxane A2 in keratinocytes.

Transparency

Commonly dusted
Min. effective
0.05%
Red flag below
0.01%

Due to its high potency, clinical efficacy is seen at very low levels (0.01%). This leads many brands to 'dust' the ingredient at minimal concentrations for marketing claims. For precision results in brightening and collagen support, we look for concentrations between 0.1% and 1%.


The Formula

Solubility
Both
Optimal pH N/A
0 7 14

Stability

Highly resistant to light, heat, and chemical oxidation. It remains stable in aqueous solutions and gels without the typical discoloration or precipitation seen in pure Vitamin C.

Synergies

  • Water-soluble polymers
  • Electrolytes
  • Glycerin
  • Broad-spectrum antioxidants

Conflicts

  • No specific chemical incompatibilities reported.

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Classified as non-cytotoxic and exceptionally well-tolerated by sensitive skin; frequently used in medical-grade Japanese 'quasi-drug' cosmetics.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A sophisticated, highly stable Vitamin C derivative that delivers significant clinical results for pigmentation and acne at remarkably low, non-irritating concentrations.


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