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CAPRYLOYL CARNOSINE.

Valuable CAS 209681-12-9 / SKIN CONDITIONING

An advanced lipoamino acid derivative that enhances the biological activity of the dipeptide L-carnosine through superior skin penetration. It acts as a high-performance stabilizer for the skin's structural framework, specifically targeting the degradation of collagen and elastin.

Anti-glycation Antioxidant Skin conditioning Collagen synthesis stimulation

Science

This molecule functions as a potent anti-glycation agent, preventing sugar molecules from cross-linking with and hardening dermal proteins like collagen. By attaching a capryloyl fatty acid chain to carnosine, the ingredient becomes more lipophilic, allowing it to bypass the skin barrier more effectively and resist degradation by carnosinase enzymes that typically neutralize standard peptides.


Research

High confidence
Effective range ≥0.004%
Optimal

0.005%

Key findings

  1. 01 Demonstrated significant up-regulation of Collagen I, III, VII, Elastin, and Hyaluronic Acid, with a specialized affinity for stimulating Collagen III (youth collagen).
  2. 02 8-week clinical assessment yielded a 94% improvement in skin texture and a 77% reduction in visible fine lines.

Transparency

Not commonly dusted
Min. effective
0.004%
Red flag below
0.001%

Due to its exceptional potency, Capryloyl Carnosine is biologically active at extremely low concentrations (as low as 0.004%). While it may look like a 'trace' ingredient on a label, these levels are clinically validated for extracellular matrix stimulation.


The Formula

Solubility
Both
Optimal pH 4.5 – 6.5
0 7 14

Stability

Exhibits superior metabolic stability compared to pure L-carnosine; it is chemically resistant to hydrolysis within standard emulsion systems.

Synergies

  • Growth factors
  • Hyaluronic Acid
  • Vitamin C
  • Matrixyl peptides

Conflicts

  • Strong oxidizing agents
  • Extreme pH environments below 3.0 or above 9.0

Safety

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Considered a safe, biomimetic peptide derivative with high skin tolerance.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A precision-engineered peptide that offers dual-action protection against glycation and structural aging at remarkably low inclusion rates.


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