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Capryloyl/Caproyl Methyl Glucamide.

Valuable CAS 1591782-62-5 / SKIN CONDITIONING, SURFACTANT - CLEANSING, SURFACTANT - EMULSIFYING, SURFACTANT - FOAM BOOSTING

A next-generation, sugar-derived surfactant that provides exceptionally gentle cleansing without compromising the skin's lipid barrier. This non-ionic glucamide is favored in precision formulations for its dual ability to remove impurities and boost the efficacy of preservative systems.

Surfactant Cleansing Agent Solubilizer Foam Booster Preservative Booster

Science

As a sugar-based surfactant with a high HLB of approximately 13, it reduces surface tension to emulsify oils and debris for easy rinsing. Its unique glucose-derived structure prevents the denaturation of skin proteins, while its molecular interaction with microbial cell walls enhances the permeability of active preservatives, allowing for lower overall preservative concentrations.


Research

High confidence
Effective range 1.85–3%
Optimal

3%

Key findings

  1. 01 NICNAS 2016 safety evaluation confirmed no public health risk in rinse-off applications at concentrations up to 3%.
  2. 02 In vitro assessments of related amino acid alkyl amides demonstrate zero dermal irritation at levels between 1.85% and 2.05%.

Transparency

Not commonly dusted
Min. effective
1%
Red flag below
0.5%

Because it functions primarily as a surfactant and solubilizer rather than an active 'hero' ingredient, it is rarely used at marketing-only 'dusting' levels; it is typically included at functional concentrations to achieve formula stability and foam quality.


The Formula

Solubility
Water
Optimal pH 4 – 9
0 7 14

Stability

Highly stable due to a robust amide bond that resists hydrolysis across a broad pH spectrum. It is cold-processable and excellent for stabilizing foam in sulfate-free systems.

Synergies

  • Fragrances
  • Essential oils
  • Preservatives
  • Sulfate-free surfactants

Safety

CIR Status
Not reviewed
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

Safety is concentration-dependent; while the raw 100% concentrate is a severe eye irritant, diluted cosmetic use at or below 3% is considered safe for rinse-off products.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An excellent, non-stripping cleansing agent that offers superior skin-feel and formulation stability compared to traditional ethoxylated surfactants.


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References