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CAPPARIS MITCHELLII LEAF EXTRACT.

Valuable CAS 1417719-28-8 / SKIN CONDITIONING

Commonly known as Wild Orange, this Australian botanical extract is a powerhouse of tryptophan and phenolic compounds designed to fortify the skin's natural moisture barrier. It functions as a bio-active shield, bridging the gap between traditional indigenous medicine and modern cellular recovery.

antioxidant soothing agent skin conditioning barrier repair

Science

This extract operates through a multi-pathway approach: it replenishes Natural Moisturizing Factors (NMFs) to stabilize the stratum corneum while its flavonoid profile—specifically luteolin and kaempferol—suppresses pro-inflammatory enzyme activity (iNOS and COX-2). Additionally, it enhances the bioavailability of Vitamin C within fibroblasts and utilizes high Ferric Reducing Antioxidant Power (FRAP) to neutralize oxidative stress.


Research

High confidence
Effective range 0.0005–5%
Optimal

2.5%

Key findings

  1. 01 Demonstrated a 40% increase in cellular Vitamin C uptake at concentrations as low as 5 µg/mL, significantly boosting collagen synthesis potential.
  2. 02 Bioactive isolates (20.38 - 42.5 µM) effectively inhibited Nitric Oxide production, confirming potent anti-inflammatory and soothing properties on a cellular level.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Due to its high efficacy in complex botanical blends at micro-doses (5 µg/mL), many brands include it at negligible levels for marketing claims. For significant barrier support and antioxidant protection, concentrations closer to 1-5% are preferred.


The Formula

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Stable in aqueous systems; however, it is thermolabile and should not be exposed to temperatures exceeding 40°C during formulation to prevent the degradation of phenolic antioxidants.

Synergies

  • Vitamin C (L-Ascorbic Acid)
  • Hyaluronic Acid
  • Niacinamide

Conflicts

  • Strong oxidizing agents
  • Highly alkaline formulations (pH > 8.0)

Safety

CIR Status
Not reviewed
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

Extensive history of traditional use and current 'clean beauty' applications show no evidence of adverse reactions or sensitization.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that excels at enhancing Vitamin C performance and soothing inflammatory pathways across all skin types.


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