Science
Mechanism of Action
This ingredient functions as a biological modulator that interacts with the skin's CB2 receptors within the endocannabinoid system to dampen inflammatory signaling (IL-6 and IL-8). Rich in Cannabisin B and phenolic compounds, it provides robust antioxidant protection while utilizing unique amino acids to accelerate the repair of the lipid barrier and support cellular regeneration.
Research
Clinical Evidence
High confidence3%
Key findings
- 01 In vitro analysis at 1.0% concentration confirmed significant DPPH radical scavenging and a measurable reduction in pro-inflammatory cytokines.
- 02 A 4-week clinical study utilizing a 3.0% concentration demonstrated a marked decrease in transepidermal water loss (TEWL) and enhanced barrier resilience.
Transparency
Dusting Analysis
Due to the marketing appeal of 'Cannabis' ingredients, it is frequently used at 'claim' levels (below 0.5%) which offer negligible biological activity. Efficacy for barrier repair and soothing requires a minimum of 1.0% to 3.0% concentration.
The Formula
Formulation
Stability
The extract is heat-sensitive; it must be incorporated during the cooling phase below 40°C to maintain the integrity of its phenolic compounds.
Synergies
- Ceramides
- Niacinamide
- Centella Asiatica
Conflicts
- Strong oxidizing agents
- Processing temperatures above 60°C
- Extreme pH environments
Safety
Safety Profile
Sprout-derived extracts are permitted for topical use provided THC content remains below 0.2%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-performance botanical for sensitive and compromised skin that bridges the gap between traditional herbal soothing and precision endocannabinoid science.
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References
Sources