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CANNABIS SATIVA SEED EXTRACT.

Valuable CAS 89958-21-4 / SKIN CONDITIONING - EMOLLIENT

A multifunctional botanical powerhouse derived from hemp seeds, specifically engineered to harmonize oil production and soothe dermal inflammation. This nutrient-dense extract bridges the gap between lipid replenishment and blemish control without the psychoactive components of the plant.

Sebum Regulator Anti-Inflammatory Antioxidant Barrier Repair Emollient

Science

This extract serves as a natural 5-alpha-reductase inhibitor, effectively blocking the hormonal pathway that triggers excessive sebum. Beyond oil control, it downregulates inflammatory cytokines to mitigate visible redness while utilizing phenolic antioxidants to shield the skin from oxidative stress and essential fatty acids to reinforce the lipid barrier.


Research

High confidence
Effective range 1–3%
Optimal

3%

Key findings

  1. 01 A 12-week clinical evaluation demonstrated that a 3% concentration significantly decreased both sebum secretion and cheek erythema (redness) with zero reported irritancy.

Transparency

Commonly dusted
Min. effective
0.5%
Red flag below
0.1%

Often included at 'label claim' levels (below 0.1%) for marketing purposes. To achieve the sebostatic and anti-redness benefits seen in clinical trials, a concentration closer to 3% is required.


The Formula

Solubility
Both
Optimal pH 4 – 7
0 7 14

Stability

Maintains structural integrity up to 65°C; however, bioactive lipids and polyphenols are sensitive to UV and oxygen, requiring opaque, airtight packaging.

Synergies

  • Niacinamide
  • Linoleic Acid
  • Ceramides

Conflicts

  • Strong oxidizing agents
  • Highly alkaline environments (pH > 9.0)

Safety

CIR Status
2024 Draft Priority List
Max tested
3%
Pregnancy
Safe
Sensitization risk Low

Cosmetic-grade extract is THC and CBD-free (or contains negligible trace amounts <0.3%), making it non-psychoactive and safe for long-term topical use.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An exceptionally versatile ingredient that excels at balancing oily, reactive skin while simultaneously providing essential barrier support.


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