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CANNABIS SATIVA FLOWER/LEAF/STEM WATER.

Valuable CAS 89958-21-4 / HAIR CONDITIONING, SKIN CONDITIONING

A refined botanical distillate derived from the aerial components of the hemp plant, offering a bio-active alternative to standard floral waters. This aqueous extract delivers trace cannabinoids and phenolic antioxidants to soothe inflammation while reinforcing the skin's moisture barrier.

Skin conditioning Anti-inflammatory Humectant Sebum regulation Antioxidant

Science

Operates through a dual-action pathway: it acts as a humectant by utilizing hydroxyl groups to bind water within the epidermis, while simultaneously modulating the NF-κB pathway. This biochemical intervention reduces the secretion of pro-inflammatory cytokines such as IL-6 and IL-8, effectively calming cutaneous stress and regulating lipid production.


Research

High confidence
Effective range 0.005–1%
Optimal

0.5%

Key findings

  1. 01 Application of 0.1%–1.0% concentrations demonstrated a 20–30% reduction in Transepidermal Water Loss (TEWL) compared to compromised skin controls.
  2. 02 Ultra-low concentrations of 0.005% showed superior inhibition of NF-κB activity and IL-8 secretion compared to purified CBD isolates.
  3. 03 In vitro testing at 20 μg/mL significantly suppressed the overproduction of MMP-1 enzymes and IL-6 induced by UVA irradiation, protecting Type I procollagen.

Transparency

Commonly dusted
Min. effective
0.005%
Red flag below
0.001%

Due to the high marketing appeal of 'Cannabis' ingredients, this water is frequently used at negligible levels for label claims. While it shows anti-inflammatory activity as low as 0.005%, concentrations below 0.1% likely fail to provide the documented barrier-repair benefits.


The Formula

Solubility
Water
Optimal pH 4 – 6
0 7 14

Stability

Highly thermolabile; degradation of active constituents accelerates above 70°C. Requires protection from UV light and should be maintained in slightly acidic environments for maximum cannabinoid stability.

Synergies

  • Hyaluronic Acid
  • Niacinamide
  • Centella Asiatica

Conflicts

  • Strong oxidizing agents
  • High processing heat
  • Extreme pH levels (>8.0 or <3.0)

Safety

CIR Status
2024 Final Priority List for review (not yet reviewed)
Max tested
5%
Pregnancy
Safe
Sensitization risk Low

In the EU, compliance with restriction II/306 is mandatory, ensuring the distillate is derived from non-prohibited parts of the plant and contains non-detectable psychotropic THC levels.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance soothing agent that outperforms CBD isolates in inflammatory modulation and provides measurable barrier support when formulated at 0.1% or higher.


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