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Moumoujus

CANNABIS SATIVA FLOWER/LEAF/STEM EXTRACT.

Valuable / ANTI-SEBUM, ANTIOXIDANT, SKIN CONDITIONING, SKIN PROTECTING

A high-performance botanical extract derived from the aerial parts of the industrial hemp plant, valued for its rich concentration of phytocannabinoids. This versatile ingredient serves as a multi-corrective agent that stabilizes the skin barrier while providing potent antioxidant protection against environmental stressors.

Summary

antioxidant antiseborrhoeic skin conditioning skin protecting

Science

Mechanism of Action

This extract operates through the cutaneous endocannabinoid system (ECS), binding to CB1 and CB2 receptors to maintain skin homeostasis. It mitigates inflammatory responses by suppressing the NF-κB pathway and IL-6 production, while simultaneously upregulating NRF2-mediated antioxidant defenses and inhibiting matrix metalloproteinases (MMPs) to preserve structural collagen.

Research

Clinical Evidence

High confidence
Effective range 0.002–0.19%
Optimal

0.1%

Key findings

  1. 01 Concentrations as low as 0.002% significantly mitigated UVA-induced procollagen reduction and suppressed MMP-1 and IL-6 expression in human fibroblasts.
  2. 02 A 0.1% concentration demonstrated robust anti-inflammatory and antioxidant activity via NF-κB inhibition and NRF2 pathway activation.
  3. 03 Human clinical trials of formulations containing this extract reported a 33% improvement in hydration levels and a 16% increase in visible skin firmness.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.002%
Red flag below
0.001%

Because biological activity is recorded at exceptionally low levels (0.002%), brands often include trace amounts purely for label marketing. For meaningful therapeutic results in anti-aging and barrier repair, concentrations closer to 0.1% are recommended.

The Formula

Formulation

Solubility
Both
Optimal pH 4.5 – 6.5
0 7 14

Stability

Highly sensitive to photo-oxidation, thermal stress, and oxygen exposure; requires opaque, airless, or amber packaging. While naturally lipophilic, modern liposomal encapsulation allows for stable integration into water-based systems.

Synergies

  • Lipids
  • Hyaluronic Acid
  • Antioxidants

Conflicts

  • Strong oxidizers

Safety

Safety Profile

CIR Status
Insufficient data
Max tested
0.19%
Sensitization risk Low

Regulatory limits are evolving; current SCCS opinions suggest a safety ceiling of 0.19% for CBD-rich extracts in dermal applications. Ensure the extract is derived from industrial hemp with compliant THC levels (<0.2-0.3%).

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

A sophisticated, multi-targeted botanical that excels at calming inflammation and protecting the dermal matrix, provided it is stabilized against light and oxygen.

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