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Moumoujus

CANAVALIA GLADIATA POD EXTRACT.

Valuable CAS - / SKIN CONDITIONING

A potent botanical extract derived from the Sword Bean pod, specifically engineered to provide multi-pathway soothing and antioxidant protection. It excels at mitigating hypersensitivity and environmental damage by stabilizing the skin’s inflammatory response.

Summary

anti-inflammatory antioxidant soothing agent skin conditioning tyrosinase inhibition

Science

Mechanism of Action

This extract functions by suppressing the PI3K/mTOR and MAPK/NF-κB signaling pathways, which are critical drivers of cellular stress. It effectively inhibits the expression of pro-inflammatory cytokines such as IL-33, IL-4, and IL-5, while its rich content of gallic and ferulic acids provides secondary benefits by neutralizing free radicals and inhibiting tyrosinase-driven pigmentation.

Research

Clinical Evidence

Medium confidence
Effective range 0.02–1%
Optimal

0.1%

Key findings

  1. 01 In vitro studies at 0.02% (200 μg/mL) demonstrated a significant reduction in allergic degranulation and PI3K/mTOR pathway activity.
  2. 02 Isolated flavonoid glycosides from the pods achieved an 86% inhibition rate of IL-33, a primary mediator of inflammatory skin conditions.
  3. 03 In vivo modeling showed a 10% decrease in inflammatory cell infiltration through targeted MAPK pathway suppression.

Transparency

Dusting Analysis

Commonly dusted
Min. effective
0.02%
Red flag below
0.005%

Because it is a botanical extract, it is frequently included at trace levels (below 0.01%) for 'label claims.' However, clinical data suggests a minimum concentration of 0.02% is required to trigger its anti-allergic and anti-inflammatory mechanisms.

The Formula

Formulation

Solubility
Water
Optimal pH 4 – 6.5
0 7 14

Stability

Contains canavalin proteins which may sediment or lose solubility in highly acidic environments below pH 3.0. The extract exhibits its best gelling and emulsifying stability in slightly acidic to neutral ranges.

Synergies

  • Niacinamide (complementary anti-inflammatory pathways)
  • Ascorbic Acid (synergistic antioxidant protection via gallic acid)
  • Hyaluronic Acid (enhances delivery of water-soluble flavonoids)

Conflicts

  • High concentrations of divalent cations like Magnesium Chloride or Calcium Chloride may cause protein precipitation.
  • Strongly acidic formulations (pH < 3.0).

Safety

Safety Profile

CIR Status
Not reviewed
Pregnancy
Safe
Sensitization risk Low

Classified as Generally Recognized as Safe (GRAS) for food consumption, suggesting a high safety ceiling for topical use. No known cosmetic restrictions from the FDA or SCCS.

Your Skin

Skin Compatibility

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Verdict

Valuable

An exceptional soothing agent for sensitive or reactive skin, provided it is formulated at concentrations above 0.02% to ensure bio-activity.

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