Science
Mechanism of Action
This extract utilizes a multi-pathway approach to skin protection: it scavenges reactive oxygen species (ROS) such as DPPH and superoxide radicals, and employs bioactive compounds like apigenin and acteoside to inhibit DNA fragmentation in fibroblasts. Furthermore, it exhibits anti-inflammatory properties by suppressing arachidonic acid-induced pathways and provides antimicrobial benefits through quorum sensing inhibition.
Research
Clinical Evidence
Medium confidence0.01%
Key findings
- 01 In vitro testing on human dermal fibroblasts demonstrated that 10-100 µg/ml significantly mitigates H2O2-induced toxicity and LDH enzyme leakage.
- 02 Antioxidant assays identified an IC50 of 20 µg/ml against DPPH radicals, indicating high potency at low concentrations.
- 03 Dose-dependent topical application showed significant reduction in chemically induced edema in animal models.
Transparency
Dusting Analysis
Because biological activity is recorded at extremely low thresholds (10 µg/ml), many formulations include this extract at sub-functional levels simply for label claims. Moumoujus identifies concentrations below 0.001% as likely 'dusting' with negligible clinical benefit.
The Formula
Formulation
Stability
The extract's polyphenol content is susceptible to oxidation; stability is maximized in aqueous or hydro-alcoholic bases when stored in opaque, airtight packaging. Use of co-solvents like glycols is recommended.
Synergies
- Glycerin
- Propanediol
- Chelating agents
Conflicts
- Strong oxidizing agents
- Extreme pH (>7.0 or <3.5)
Safety
Safety Profile
Classified as safe under the European COSMILE database. As with all botanical extracts, individuals with specific flower allergies should patch test prior to use.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A highly efficient antioxidant and fibroblast-protector that provides measurable cellular benefits at micro-dosages, provided the formulation maintains an optimal acidic pH.
Related
Similar Ingredients
Finding similar ingredients…