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CAMPHOR SULFONIC ACID.

Valuable CAS 5872-08-2 / NOT REPORTED

A sophisticated, water-soluble organic UV filter recognized for its exceptional photostability and specialized protection against UVA radiation. It is a cornerstone ingredient in high-performance sunscreens, valued for its ability to prevent photo-induced aging and DNA damage without the instability common in older chemical filters.

UV Filter Sunscreen Agent Photo-stabilizer

Science

This molecule acts as a precision UVA absorber, peaking at 345 nm. Upon exposure to UV light, it undergoes photoisomerization—a process where it absorbs photon energy and converts it into harmless thermal energy. This mechanism is inherently safer than filters that generate free radicals, as it prevents the oxidative stress typically associated with UV exposure.


Research

High confidence
Effective range 2–10%
Optimal

5%

Key findings

  1. 01 Clinical data from FDA NDA 21-502 indicates that 2% concentrations effectively prevent photo-induced dermatoses and protect against UVA-specific cellular damage.
  2. 02 In vivo research demonstrated a tumor protection factor of 2.4 at a 5% concentration, significantly outperforming standard UVB filters like 2-EHMC in preventing carcinogenesis.
  3. 03 Pharmacokinetic studies show that even at a maximal 10% usage rate, systemic absorption remains extremely low, though it warrants monitoring according to 2020 FDA safety thresholds.

Transparency

Not commonly dusted
Min. effective
2%
Red flag below
0.5%

To achieve biological efficacy for UVA protection, a minimum of 2% is typically required. Inclusion below 1% is generally insufficient for photoprotection and may be used for marketing claims rather than functional defense.


The Formula

Solubility
Water
Optimal pH 5 – 7.5
0 7 14

Stability

Highly photostable. It acts as a stabilizer for other volatile filters. The raw material is strongly acidic and requires precise neutralization to a physiological pH during the manufacturing process.

Synergies

  • Avobenzone (provides structural stabilization)
  • Oil-soluble UV filters (creates a more uniform protective film)

Conflicts

  • Cationic surfactants
  • Strong oxidizing agents
  • Unneutralized strong bases

Safety

CIR Status
Not reviewed
Max tested
10%
Sensitization risk Low

Approved up to 10% in the EU and Australia. US use is restricted to specific approved New Drug Applications (NDAs). It is noted for its low potential for contact allergy or irritation.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

An elite, photostable UVA filter that offers reliable protection against photo-aging and skin cancer when formulated at or above 2%.


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