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CAMELLIA JAPONICA SEED EXTRACT.

Valuable CAS 223748-13-8 / SKIN CONDITIONING

A nutrient-dense botanical powerhouse derived from the Tsubaki flower, renowned for its dual-action ability to deeply hydrate and provide robust environmental defense. This refined extract serves as a multifunctional lipid-replenisher that targets both the structural integrity and the external resilience of the skin barrier.

Skin conditioning Emollient Antioxidant Anti-glycation Barrier repair

Science

This extract operates as a biological fibroblast activator, upregulating the synthesis of Type I procollagen and natural hyaluronic acid. It delivers potent SOD-like antioxidant activity to neutralize oxidative stress while simultaneously inhibiting MMP-1 enzymes to prevent collagen breakdown and blocking the glycation pathways that lead to skin rigidity.


Research

High confidence
Effective range 0.01–1%
Optimal

1%

Key findings

  1. 01 A 1% topical application demonstrated a significant reduction in transepidermal water loss (TEWL) and protected dermal structures against UV-B induced damage.
  2. 02 In vitro testing at a 0.01% concentration showed a measurable inhibition of Advanced Glycation End-products (AGEs) in human fibroblasts.
  3. 03 Oral supplementation of 200mg daily resulted in a 14% increase in facial hydration levels over an 8-week period.

Transparency

Commonly dusted
Min. effective
0.1%
Red flag below
0.05%

Because it is a prestigious botanical, it is frequently included at 'label-claim' levels (below 0.1%) where its anti-glycation benefits begin, but its significant barrier-repair and moisture-retaining properties require concentrations closer to 1%.


The Formula

Solubility
Both
Optimal pH 5 – 8
0 7 14

Stability

Susceptible to oxidation due to high lipid and saponin content; requires light-protected packaging and the addition of chelating agents like Disodium EDTA to maintain bioactivity.

Synergies

  • Vitamin E
  • Hyaluronic Acid
  • Chelating agents

Conflicts

  • Extreme pH environments
  • Strong oxidizing agents

Safety

CIR Status
Safe as used
Max tested
10%
Pregnancy
Safe
Sensitization risk Low

Classified as GRAS (Generally Recognized as Safe) and conforms to Japanese JSQI standards for high-tolerance quasi-drug ingredients.


Your Skin

Yes Normal
Yes Dry
Yes Oily
Yes Sensitive
Irritancy Low
Comedogenicity Low

Our Assessment

Valuable

A high-performance botanical that bridges the gap between traditional emolliency and modern molecular anti-aging.


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