Science
Mechanism of Action
This extract operates through a dual-action pathway: first, it significantly inhibits pro-inflammatory markers like PGE2 and TNF-alpha to soothe dermal stress; second, it optimizes cellular respiration and ATP production. It also stimulates the synthesis of fibronectin, an essential glycoprotein that maintains the integrity of the extracellular matrix.
Research
Clinical Evidence
High confidence0.08%
Key findings
- 01 Observed a 40-57% reduction in PGE2 induction and a 24-35% decrease in TNF-alpha secretion, confirming potent anti-inflammatory properties.
- 02 Demonstrated significant enhancement in skin cell resistance to hypoxia and boosted energy metabolism (ATP production).
Transparency
Dusting Analysis
Because this ingredient is highly effective at micro-concentrations (even 0.04% shows significant results), brands often include it at negligible levels (below 0.005%) just for marketing claims. Effectiveness requires at least 0.01% of the pure extract.
The Formula
Formulation
Stability
Demonstrates high stability in aqueous solutions, particularly when stabilized in a glycerol-water carrier (80:20 ratio).
Synergies
- Glycerin
- Antioxidants
- Peptides
Safety
Safety Profile
While the raw trade material is often a 4% concentration, the final safe and effective usage in skincare finished products is capped near 0.1%.
Your Skin
Skin Compatibility
Our Assessment
Verdict
A high-precision botanical active that provides measurable anti-inflammatory benefits and cellular energy support at very low concentrations.
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References
Sources